A PRIMATE MODEL OF GUT, IMMUNE, AND CNS RESPONSE TO CHILDHOOD VACCINES

儿童疫苗的肠道、免疫和中枢神经系统反应的灵长类动物模型

• 批准号: 8172766
• 负责人: GENE P. SACKETT
• 金额: $ 15.51万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172766
• 关键词: Affect; Autistic Disorder; Child; Childhood; Computer Retrieval of Information on Scientific Projects Database; Development; Diagnosis; Funding; Grant; Immune; Immunologics; Institution; Modeling; Primates; Regimen; Research; Research Personnel; Resources; Source; Symptoms; Toxic effect; United States; United States National Institutes of Health; Vaccines; developmental disease; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Diagnoses of childhood developmental disorders involving autism-spectrum symptoms are increasing, estimated to affect 1 in 100 children in the United States. Childhood vaccines have been hypothesized to be contributory factors to this increase. The childhood vaccine regimen has an experimentally unstudied potential for cumulative and synergistic toxicities and possible immunologic interference to normal development.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 涉及自闭症谱系症状的儿童发育障碍的诊断数量正在增加，估计在美国每 100 名儿童中就有 1 人受到影响。 据推测，儿童疫苗是导致这一增长的因素。 儿童疫苗方案具有未经实验研究的潜在累积和协同毒性以及可能对正常发育的免疫干扰。