TRAINING IN FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY

傅里叶变换离子回旋共振质谱培训

• 批准号: 8170885
• 负责人: CHI-WEI LIN
• 金额: $ 0.58万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170885
• 关键词: Biochemistry; Bioinformatics; Boston; Carbohydrates; Chemistry; Collaborations; Computer Retrieval of Information on Scientific Projects Database; England; Fourier Transform; Fourier transform ion cyclotron resonance; Funding; Grant; HRAS gene; Human; Institution; Left; Mass Spectrum Analysis; Medicine; Modification; Oxidative Stress; Peptides; Positioning Attribute; Postdoctoral Fellow; Research; Research Personnel; Research Project Grants; Resources; SHFM1 gene; Scientist; Source; Techniques; Training; United States National Institutes of Health; Universities; Washington; Work; base; graduate student; instrument; medical schools; meetings; professor; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. One of the objectives of this program is to train new graduate students and professional scientific researchers in new techniques. One such technique which we have focused on is Fourier transform mass spectrometry. Since the departure of Dr. Peter O'Connor in Jan 2009 to become a tenured full professor in the Department of Chemistry at the University of Warwick, Coventry, England, Dr. Cheng Lin has assumed responsibility for training in FTMS, and FTMS-based research projects. He is now a research assistant professor in the Department of Biochemistry at Boston University School of Medicine, and the Assistant Director of the Resource. A graduate student from the FTMS research group, Konstantine Aizikov, defended his Ph. D. thesis in November 2009, and remains at the MSR as a postdoctoral associate working on glyco-bioinformatics. A former postdoc, Dr. Weidong Cui left in May 2009 to take a staff scientist position at Washington University in St. Louis. In September 2009, Yuhuan Ji joined the FTMS group as a graduate student, working on human H-ras modifications under oxidative stress, in collaboration with Dr. Cohen's group in the Department of Medicine. In December 2009, Dr. Yiqun Huang joined the FTMS group as a postdoctoral fellow, taking on the mechanistic studies of ECD of peptides and carbohydrates. In January 2010, the newly arrived 12 T Bruker solariX FT-ICR instrument, acquired through a high-end shared instrument grant, was certified to meet all specs in January 2010. Since then, several postdoctoral research associates of the Resource and senior graduate students from the FTMS group have been properly trained to use this new instrument for a diversity of research projects.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 该项目的目标之一是培训新研究生和专业科学研究人员掌握新技术。 我们关注的一项此类技术是傅里叶变换质谱法。 自 Peter O'Connor 博士于 2009 年 1 月离职成为英国考文垂华威大学化学系终身正教授以来，Cheng Lin 博士一直负责 FTMS 的培训，以及基于 FTMS 的培训。研究项目。他现在是波士顿大学医学院生物化学系的研究助理教授，兼资源部助理主任。 FTMS 研究小组的研究生 Konstantine Aizikov 于 2009 年 11 月通过了博士学位论文答辩，并继续在 MSR 担任博士后，从事糖生物信息学研究。 崔卫东博士曾是一名博士后，于 2009 年 5 月离职，前往圣路易斯华盛顿大学担任研究员科学家职位。 2009年9月，季玉环以研究生身份加入FTMS小组，与医学系Cohen博士小组合作，研究氧化应激下的人类H-ras修饰。 2009年12月，黄益群博士作为博士后加入FTMS课题组，从事肽和碳水化合物的ECD机理研究。 2010 年 1 月，通过高端共享仪器赠款购买的新抵达的 12 T Bruker SolariX FT-ICR 仪器于 2010 年 1 月被认证满足所有规格。此后，该资源的几位博士后研究员和高年级研究生来自 FTMS 小组的人员已接受过适当的培训，可以使用这种新仪器进行各种研究项目。