IGF::OT::IGF NHP TISSUE BANK

IGF::OT::IGF NHP 组织库

• 批准号: 8742069
• 负责人: Joseph W. Kemnitz
• 金额: $ 10.06万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2014-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8742069
• 关键词: Animal Housing; Animals; Archives; Communities; Ensure; Freezing; Human; Macaca mulatta; Modeling; Molecular; Protocols documentation; Research; Research Personnel; Resources; Techniques; Testing; Tissue Banking; Tissue Banks; Tissues; aged; nonhuman primate; sample fixation

This will provide a new research resource to many investigators and contribute to a reduction in the number of NHP needed by the research community since multiple investigators will be able to take advantage of each animal. The tissue will allow investigators to test hypotheses in a model closely related to humans by providing access to NHP tissue without the expense of obtaining and housing the animals. This is an extremely important aspect of this project, as the supply of NHP in general, and rhesus macaques in particular, is very limited. The tissues will be collected under strictly controlled protocols to ensure the integrity of the tissue. Tissue will be flash-frozen without fixation or fixed and embedded, to fit the needs of a wide-range of molecular and histochemical techniques.

这将为许多研究人员提供新的研究资源，并为减少研究界所需的NHP数量的数量做出贡献，因为多个研究人员将能够利用每种动物。该组织将允许研究人员通过提供与人类密切相关的模型中的假设，通过提供对NHP组织的访问而无需获得和安置动物的费用。这是该项目的一个极为重要的方面，因为NHP的供应总体上，尤其是恒河猕猴的供应非常有限。组织将在严格控制的方案下收集，以确保组织的完整性。组织将在没有固定或固定和嵌入的无固定性或嵌入的情况下进行闪烁，以满足大范围的分子和组织化学技术的需求。