Administrative

行政的

基本信息

批准号：
8516872
负责人：
Eric Hunter
金额：
$ 44.63万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-01 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8516872
关键词：
AIDS Vaccines Acquired Immunodeficiency Syndrome Advisory Committees Animals Annual Reports Antibodies Avidity B-Lymphocytes Binding Budgets Cellular biology Communication Consultations Cytotoxic T-Lymphocytes DNA DNA Vaccines DNA/MVA vaccine Data Data Analyses Data Base Management Databases Decision Making Development Dose Ensure Epidemic Goals Granulocyte-Macrophage Colony-Stimulating Factor HIV HIV Envelope Protein gp120 Immune Immune response Immunization Immunoglobulin A Immunology Individual Institution Instruction Intellectual Property Leadership Legal patent Macaca Mediation Peptide Vaccines Peptides Production Proteins Publications Publishing Reagent Research Research Personnel Research Project Grants Resources SIV Sampling Science Specimen T cell response T-Lymphocyte Teleconferences Tissue Sample United States National Institutes of Health Vaccines Viral Virus base data management data sharing meetings neutralizing antibody nonhuman primate operation programs rectal repository response success transmission process vaccine development

项目摘要

The Administrative Core will provide overall leadership and coordination for the Consortium. Through its specimen repository and database management functions, it will ensure that there is a coordinated and efficient utilization of non-human primate samples derived from projects 1, 2 and 3. It will be responsible for collecting, storing and analyzing samples from the individual Research Programs and Cores within the Consortium, and will provide statistical support for data analysis, in order to ensure that effective and functional collaborative science results. The Administrative Core will maintain budgets and oversee any rebudgeting that may be needed to meet Consortium goals. The Core, in conjunction with the individual investigators and an external advisory committee, will ensure that established research milestones are met. It will organize monthly investigator meetings and teleconferences to ensure that regular opportunities for communication between the scientific components ofthe Consortium are established. It will organize the production and procurement of DNA and MVA vaccine components, as well as coordinate SIV peptide acquisition from the NIH AIDS Repository for individual research projects and cores. The Core will provide logistical support for timely sharing of data internally and externally through publications and presentations according to the Data Sharing Plan, and manage intellectual filings and MTAs as well as co-ordinate the distribution of unique resources under appropriate MTAs. Overall, the Administrative Core will provide the

行政核心将为联盟提供全面领导和协调。通过其样本库和数据库管理功能，它将确保项目1、2和3中获得的非人类灵长类动物样本得到协调和有效的利用。它将负责收集、存储和分析来自各个研究的样本联盟内的计划和核心，将为数据分析提供统计支持，以确保有效和功能性的协作科学结果。行政核心将维持预算并监督实现联盟目标可能需要的任何重新预算。核心与个别研究人员和外部咨询委员会一起，将确保达到既定的研究里程碑。它将每月组织一次研究者会议和电话会议，以确保联盟科学组成部分之间建立定期沟通的机会。它将组织 DNA 和 MVA 疫苗成分的生产和采购，并协调从 NIH 艾滋病存储库获取 SIV 肽，用于个别研究项目和核心。该核心将根据数据共享计划，通过出版物和演示文稿，为内部和外部及时共享数据提供后勤支持，并管理知识档案和 MTA，并根据适当的 MTA 协调独特资源的分配。总体而言，行政核心将提供