National Initiative for Minority Involvement in Neurological Clinical Trials

少数民族参与神经临床试验的国家倡议

基本信息

批准号：
8529216
负责人：
BERNADETTE Marie BODEN-ALBALA
金额：
$ 72.09万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-22 至 2013-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8529216
关键词：
ARHGEF5 gene Academic Medical Centers Address Attitude Behavioral Bioethics Bioinformatics Biological Clinic Clinical Clinical Research Clinical Trials Collaborations Collection Communities Community Health Community Hospitals Consensus Country Educational Curriculum Enrollment Family Goals Guidelines Hispanics Hospitals Human Resources Individual Institutes Institution Instruction Latino Lead Literacy Programs Literature Minority Minority Groups Neurologic New York Not Hispanic or Latino Observational Study Participant Perception Population Positioning Attribute Practice Guidelines Presbyterian Church Procedures Randomized Clinical Trials Recruitment Activity Relative (related person)Research Research Infrastructure Research Personnel Resources Sampling Specimen Surveys Testing Training Translational Research U-Series Cooperative Agreements Universities Work community planning comparative effectiveness effectiveness research experience health disparity health literacy improved innovation instrument literacy member minority health multidisciplinary programs response success tool

项目摘要

Poor recruitment and retention of minority populations in clinical research, and clinical trials in particular, continues to be a significant barrier in the reduction of health disparities. Although we have been successful we realize that there are few best-practice guidelines which have systematically outlined successful strategies to promote and sustain successful recruitment and retention of minority populations. This application was prepared in response to RFA-MD-11-005. NIMHD Resource-Related Minority Health and Health Disparities Research (U24). This proposal will specifically address focus "(a) Bioethics Research Infrastructure Initiative". Our goal is to integrate and expand existing resources to refine and support a comprehensive multidisciplinary program to enhance clinical trial recruitment and retention of minority individuals. This program will be lead by a partnership between the Community Engagement Core Resource ofthe Irving Institute for Clinical Translational Research (IICTR; UL1 RR024156) and the Northern Manhattan Center of Excellence in Minority Health and Health Disparities (NOCEMHD; P60 MD000206). NOCEMHD also includes the Northern Manhattan Center of Excellence for Comparative Effectiveness Research (CER) to Eliminate Disparities (NOCERED; P60 MD000206PI-08S1). The CECR. NOCEMHD, and NOCERED currently conduct and support recruitment of minorities for clinical trials, and are central resources for minority recruitment in research in Northern Manhattan. We will call this proposed program the Northern Manhattan Initiative for Minority involvement in Clinical Trials (NIMICT). The specific aims (SA) of NIMICT are: 1) Develop, pilot, and evaluate a toolkit of "Best Practices" (instruments and procedures) for the conduct of successful recruitment and retention of racial and ethnic minorities in clinical trials; 2) Expand and refine innovative recruitment strategies recently implemented at CUMC for general research for use in minority recruitment and retention in clinical trials, including a community health worker program and a health literacy program; 3) Building on the experience from SAs 1,2 and in collaboration with relevant stakeholders, NIMHD, and other national centers, disseminate the experience of our initiative and seek consensus to develop local and national guidelines for recruitment and retention of minorities in clinical trials. As part of the cooperative agreement, we expect significant collaboration with NIMHD and with other programs in the country with a similar focus.

在临床研究中，尤其是临床试验中的少数族裔招募和保留不良，尤其是在减少健康差异方面仍然是一个重大障碍。虽然我们已经成功了我们意识到，有系统概述成功的最佳实践指南促进和维持成功招募和保留少数民族的策略。这响应RFA-MD-11-005准备申请。 NIMHD与资源有关的少数民族健康和健康差异研究（U24）。该建议将专门针对重点”（a）生物伦理学研究基础设施倡议”。我们的目标是整合和扩展现有资源，以完善和支持全面的多学科计划，以增强少数族裔的临床试验招聘和保留个人。该计划将由社区参与核心资源之间的合作伙伴关系领导欧文临床转化研究所（IICTR; UL1 RR024156）和北部曼哈顿少数民族健康与健康差异卓越中心（Nocemhd; p60 MD000206）。 Nocemhd还包括曼哈顿北部卓越中心的比较有效性消除差异的研究（CER）（Nocered; p60 MD000206PI-08S1）。 CECR。 nocemhd，当前的临床试验少数族裔的招募和支持是中心的曼哈顿北部研究的少数族裔招募资源。我们将此建议的程序称为曼哈顿北部少数群体参与临床试验（NIMICT）。特定目的（SA）的 NIMICT是：1）开发，试行和评估“最佳实践”工具包（工具和程序）在临床试验中，成功招募和保留种族和少数民族； 2）扩展和改进了最近在CUMC实施的创新招聘策略，以供一般研究临床试验中的少数族裔招聘和保留，包括社区卫生工作者计划和健康扫盲计划； 3）建立SAS 1,2的经验，并与相关利益相关者合作， NIMHD和其他国家中心，分发了我们倡议的经验，并寻求共识制定临床试验中少数民族招募和保留少数民族的地方和国家准则。作为一部分合作协议，我们期望与NIMHD以及与其他计划合作以类似重点的国家。