The Southwest National Primate Research Center

西南国家灵长类动物研究中心

• 批准号: 8705077
• 负责人: Kenneth Parkhurst Trevett
• 金额: $ 39.9万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-06 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8705077
• 关键词: Aging; Biomedical Research; Breeding; Callithrix; Callithrix jacchus jacchus; Chronic Disease; Commit; Communicable Diseases; Communities; Development; Disease; Focus Groups; Foundations; Genetic Research; Genomics; Genotype; Grant; Health; Institution; Macaca; Macaca mulatta; Mission; Neonatal; Pan Genus; Papio; Pharmaceutical Preparations; Population; Primates; Research; Research Infrastructure; Research Personnel; Resources; Services; Translational Research; base; biodefense; disorder prevention; gene discovery; genetic resource; improved; innovation; meetings; nonhuman primate; programs; stem cell biology; vaccine development

The objective of this proposal is to continue support of the infrastructure of the Southwest National Primate Research Center (SNPRC). The SNPRC is located on the campus of the Southwest Foundation for Biomedical Research, its host institution. The SNPRC maintains over 4,000 nonhuman primates, primarily baboons, macaques, marmosets, and chimpanzees. It maintains large breeding populations of baboons, rhesus macaques, and common marmosets. During the current grant period, the SNPRC provided resources to 290 investigators from 35 states. The base grant is composed of four types of components: Administration, Primate Resources, Veterinary Resources, and Research Resources. The Research Resource components and the research programs that utilize them are divided among four Focus Groups: Infectious Diseases and Biodefense, Chronic Diseases, Development and Aging, and Genomics. The mission of the SNPRC is "To improve the health of our global community through innovative biomedical research with nonhuman primates." Consistent with this mission, the SNPRC is committed to translational research and is a partner in two CTSA applications that are in review. The administration, primate resource, veterinary resource, and research resource infrastructures supported by the base grant enable the SNPRC to be responsive to national biomedical research needs and to accommodate investigators who want to access Center resources for collaborative research purposes. Special, and in some cases unique, strengths of the SNPRC are a wide variety of primate species to meet diverse research needs; the largest pedigreed and genotyped population of nonhuman primates available for genetic research; broad research opportunities with the largest chimpanzee population at any National Primate Research Center; ABSL-3 and ABSL-4 facilities; research emphasis and expertise on gene discovery for common chronic diseases, development of vaccines and drugs for infectious diseases, preventions and treatments of neonatal diseases, and stem cell biology; and service as a national resource for genetic management of nonhuman primates.

该提议的目的是继续支持西南民族的基础设施 灵长类动物研究中心（SNPRC）。 SNPRC位于西南基金会的校园 生物医学研究，其主机机构。 SNPRC维护4,000多个非人类灵长类动物，主要是 狒狒，猕猴，果酱和黑猩猩。它维持大量的狒狒种群 恒河猕猴和常见的棉花糖。在当前赠款期间，SNPRC提供了 来自35个州的290名调查人员的资源。基本赠款由四种类型的组件组成： 管理，灵长类动物资源，兽医资源和研究资源。研究 资源组成部分和利用它们的研究计划分为四个焦点组： 传染病和生物疾病，慢性疾病，发育和衰老以及基因组学。 SNPRC的使命是“通过创新来改善我们全球社区的健康 与非人类灵长类动物的生物医学研究。“与此任务一致，SNPRC致力于 翻译研究，是正在审查的两个CTSA应用程序中的合作伙伴。政府， 基本赠款支持的灵长类动物资源，兽医资源和研究资源基础架构 使SNPRC能够响应国家生物医学研究需求并适应 希望用于协作研究目的的中心资源的调查人员。特殊和 在某些情况下，SNPRC的优势独特，是各种各样的灵长类动物，可满足多种研究 需求；可用于遗传的最大的非人类灵长类动物的基因分型人群 研究;任何国家灵长类动物的黑猩猩人口最大的研究机会 研究中心； ABSL-3和ABSL-4设施；研究重点和专业知识对基因发现的专业知识 常见的慢性疾病，用于传染病的疫苗和药物的开发，预防和 新生儿疾病和干细胞生物学的治疗；和服务作为遗传资源的国家资源 非人类灵长类动物的管理。