Stigma Associated with a High-Risk State for Psychosis

与精神病高风险状态相关的耻辱

• 批准号: 8222135
• 负责人: LAWRENCE H YANG
• 金额: $ 51.48万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-22 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8222135
• 关键词: Achievement; Address; Adolescent; Adult; Affect; Attitude; Behavior; Benchmarking; Clinical Research; Costs and Benefits; Country; Data; Development; Diagnosis; Diagnostic and Statistical Manual; Early Diagnosis; Early identification; Family; Family member; Goals; Hospitalization; Individual; Intervention; Investigation; Life; Measures; Outcome; Perception; Phase; Policies; Psychotic Disorders; Recovery; Relative (related person); Research; Research Personnel; Risk; Schizoaffective Disorders; Schizophrenia; Schools; Severities; Social Functioning; Social Network; Source; Staging; Stigmata; Symptoms; Time; comparison group; experience; follow-up; high risk; peer; prevent; psychologic; psychological outcomes; response; social; social stigma; treatment adherence; young adult

PROJECT SUMMARY We propose the first study to systematically examine any potential effects of stigma associated with the new 'high risk for psychosis' ('HRP') designation, a groundbreaking development in the earliest identification of psychotic signs that enables efforts to prevent psychosis. Concerns of stigma towards the new HRP status have been expressed because this designation has the potential to activate the same severe social ramifications known to be associated with an identification of 'psychosis'. Stigma may be an unnecessary risk especially because the majority of those identified as HRP even in the absence of intervention do not go on to develop psychosis. Further, the HRP designation is being used in over 6 countries (including the U.S.) and there is current debate to include it officially within the DSM 5 in 2013. Because no evidence exists regarding stigma of the HRP, we bring together expertise from two well-established research teams that have experience in treating and following HRP individuals and their family members with that of recognized researchers in stigma and the early course of psychosis. We propose a comprehensive approach to assessing stigma experiences among a HRP group (n= 196) and associated 'family attitudes' among family members (n= 155) at initial HRP identification and then at 6 months follow-up. We compare the stigma experiences of the HRP group with that of a first episode non-affective psychosis group (FEP; n= 100) who act as a benchmark for severe stigma. We examine stigma of the HRP designation at baseline, how any stigma may increase or decrease over time, and how this stigma compares with that of an FEP group. We further assess longitudinal impacts of HRP stigma and 'family attitudes' upon changes in psychological, social, and developmental outcomes in the HRP group. This research promises to greatly inform interventions to counter stigma at its earliest stages and maximize opportunities for people at HRP to attain developmental goals leading to adulthood. Further, removing or ameliorating this concern of stigma is crucial, as HRP identification is a potentially transformative means of preventing and treating schizophrenia, thus reducing burden for psychosis worldwide.

项目摘要 我们提出了第一项研究，以系统地检查与新的污名的任何潜在影响 “精神病高风险”（“ HRP”）指定，这是最早确定的开创性发展 精神病的迹象，能够预防精神病。对新HRP状态的污名的担忧 之所以表达，是因为此名称有可能激活相同的严重社会 已知与“精神病”识别有关的后果。污名可能是不必要的风险 特别是因为即使在没有干预的情况下，大多数被确定为HRP的人都没有继续 发展精神病。此外，HRP名称正在超过6个国家（包括美国）和 目前有辩论将其正式纳入2013年的DSM 5。 HRP的污名，我们从两个有经验的研究团队中汇集了专业知识 在治疗和关注HRP个人及其家人的过程中 污名和精神病的早期过程。我们提出了一种评估污名的全面方法 HRP组（n = 196）和家庭成员之间相关的“家庭态度”（n = 155）之间的经验 最初的HRP识别，然后在6个月的随访中。我们比较HRP的污名经历 小组与第一集非影响精神病小组（FEP; n = 100）的小组，他们充当基准 严重的污名。我们检查了基线时HRP名称的污名，任何污名如何增加或 随着时间的流逝而减少，以及这种污名与FEP组的污名相比。我们进一步评估纵向 HRP污名和“家庭态度”对心理，社会和发展的变化的影响 HRP组的结果。这项研究有望极大地告知干预措施，以应对其污名 最早的阶段，并最大程度地利用HRP的人实现发展目标的机会 成年。此外，消除或改善对污名的关注至关重要，因为HRP识别是 预防和治疗精神分裂症的潜在变革手段，从而减轻了负担 全球精神病。