FitFab 4 Survivors

FitFab 4 幸存者

• 批准号: 8291255
• 负责人: Bernard F Fuemmeler
• 金额: $ 17.89万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8291255
• 关键词: Acute Lymphocytic Leukemia; Adolescent; Adopted; Adult; Advocacy; Aftercare; Age; Area; Attitude; Behavior; Behavioral Research; Belief; Body mass index; Cancer Control; Cancer Survivor; Car Phone; Cardiovascular Diseases; Cartoons; Cerebrovascular Disorders; Child; Child Psychology; Childhood Acute Lymphocytic Leukemia; Cognitive; Computer software; Counseling; Data; Development; Diet; Diet Monitoring; Dietary intake; Eating; Effectiveness; Elements; Epidemiology; Expectancy; Fatty acid glycerol esters; Feasibility Studies; Feedback; Focus Groups; Frequencies; General Population; Goals; Health; Health Promotion; Health behavior; Health behavior change; High Prevalence; Hospitals; Insulin Resistance; Intervention; Interview; Knowledge; Learning; Life Style; Measures; Mediator of activation protein; Methods; Monitor; Motivation; Obesity; Osteoporosis; Outcome; Overweight; Parents; Participant; Patient Self-Report; Pediatric Hematology/Oncology; Phase; Physical activity; Prevention; Professional counselor; Protocols documentation; Qualitative Research; Randomized; Randomized Controlled Trials; Recommendation; Relative (related person); Research; Research Design; Rewards; Risk; Self Efficacy; Social Network; Social support; Sports; Staging; Survivors; Target Populations; Technology; Telephone; Testing; Text; Token Economy; Visit; Waiting Lists; Weight; Weight Gain; Weight maintenance regimen; arm; base; calcium intake; cancer prevention; child adoption; childhood cancer survivor; cohort; computer science; cost effectiveness; design; follow-up; fruits and vegetables; good diet; improved; innovation; meetings; member; novel; obesity risk; post intervention; prevent; programs; response; social; social cognitive theory; software development; success; survivorship; therapy design; therapy development; tool; virtual

DESCRIPTION (provided by applicant): Advancements in treatment for childhood Acute Lymphoblastic Leukemia (ALL) have resulted in a growing cohort of survivors. Many survivors of childhood ALL do not meet recommendations for physical activity or healthy diet, and are at risk for obesity and overweight as they move into adulthood. These lifestyle behaviors have the potential to complicate health problems for which these survivors are already at risk. To date, there are few efficacious interventions available to assist this group of cancer survivors wishing to adopt healthier lifestyles. Because survivors of ALL are geographically dispersed and relatively small in numbers, interventions will need to be developed to be delivered at a distance. The primary aim of this proposal is the development and feasibility testing of an innovative intervention designed to promote healthy dietary intake, increase physical activity, and prevent weight gain that can be delivered using smarthphone technology. The intervention will be developed for adolescent survivors of childhood ALL ages 13-19 years who are at least 2 years off treatment. The intervention will include the use of a specialized, study-designed smartphone application (app), weekly supportive counseling, and materials for parents to help them support their child as they take part in the intervention. The app will include tools for near effortless self-monitoring of diet, physical activity, and weight; motivational messages and the use of a virtual token-economy to encourage participation; and a social-networking component that will allow participants to support one another. Elements of social- cognitive theory will be used to develop the app and intervention. A formative phase focused on intervention and software development will be followed by a pilot test of the intervention among 40 adolescents randomized to either a wait-list control (WLC) arm or the intervention arm. Outcomes will include quality of dietary intake, physical activity, body-mass index and social cognitive mediators of health behavior change. The investigative team has expertise in areas of pediatric psychology, pediatric hematology-oncology, obesity epidemiology/prevention, and computer science and thus, is well poised to undertake the proposed research. The successful completion of this proposal will set the stage for a larger multi-center randomized controlled trial in which we will evaluate the efficacy and cost-effectiveness of our intervention.

描述（由申请人提供）：儿童期急性淋巴细胞白血病的治疗进展（ALL）导致了越来越多的幸存者。许多童年的幸存者都不符合体育锻炼或健康饮食的建议，并且在成年后有肥胖和超重的风险。这些生活方式行为有可能使这些幸存者已经处于危险中的健康问题复杂化。迄今为止，几乎没有有效的干预措施可以帮助这群希望采用更健康生活方式的癌症幸存者。由于所有人的幸存者在地理上分散并且数量相对较小，因此需要开发干预措施才能在距离处进行交付。该提案的主要目的是对旨在促进健康饮食摄入量，增加体育锻炼并防止可以使用Smarthphone技术进行的创新干预措施的开发和可行性测试。该干预措施将针对童年的青少年幸存者开发，所有年龄在13-19岁之间至少有2年的治疗。干预措施将包括使用专门的，学习设计的智能手机应用程序（APP），每周的支持咨询以及父母的材料，以帮助他们在参加干预时抚养孩子。该应用程序将包括几乎轻松自我监控饮食，体育锻炼和体重的工具；激励性信息和使用虚拟令牌经济来鼓励参与；以及一个社交网络组件，将允许参与者互相支持。社会认知理论的要素将用于开发应用程序和干预措施。重点介绍干预和软件开发的形成阶段将进行对40名随机分配给候补名单控制（WLC）组或干预部门的干预措施的试点测试。结果将包括饮食摄入量，体育锻炼，身体质量指数和健康行为行为改变的社会认知介体。调查团队在儿科心理学，小儿血液肿瘤学，肥胖流行病学/预防以及计算机科学领域具有专业知识，因此有很好的准备进行拟议的研究。该提案的成功完成将为更大的多中心随机对照试验奠定了基础，我们将评估干预的疗效和成本效益。