Coils for Human Whole Body Imaging at 7T

用于 7T 人体全身成像的线圈

• 批准号: 8707801
• 负责人: John T Vaughan
• 金额: $ 50.25万
• 依托单位: LIFE SERVICES, LLC
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8707801
• 关键词: Acceleration; Achievement; Amplifiers; Attenuated; Biomedical Research; Body Image; Bypass; Clinical; Coiled Bodies; Communities; Data Collection; Development; Devices; Disease; Elements; Engineering; Frequencies; Goals; Grant; Head; Health; Heating; Human; Human body; Image; Indium; Life; Magnetic Resonance Imaging; Manufacturer Name; Marketing; Measures; Morphologic artifacts; Noise; Patients; Pattern; Phase; Radio; Research; Research Personnel; Resolution; Signal Transduction; Small Business Technology Transfer Research; Solutions; Speed; System; Technology; Testing; Therapeutic Intervention; Time; Translating; Variant; Water; Work; absorption; base; body system; clinical application; cost; design; ergonomics; human tissue; improved; innovation; magnetic field; neuroimaging; new technology; prototype; public health relevance; radiofrequency; success; whole body imaging

For this Phase II STTR proposal, the investigators plan to develop and commercialize the radiofrequency (RF) coil technology to make 7T body MRI possible, and to translate this new technology to vastly improve 3T clinical MRI as well. In the Phase I project leading to this proposal, all specific aims were accomplished to demonstrate the feasibility of safely and successfully imaging the human body for the first time with commercially available technology at 7T. This technology incorporated a number of innovations including automatic tuning and matching, and multi-channel transmit RF field shimming. Unlike the whole body coil built into the bore of clinical magnets, the RF coil technology developed here is easily retrofitted to existing systems, atop the patient table and fitting closely to the body for improved efficiency. The Phase II project proposed will deliver an improved commercial package of this device with the built-in, multi-channel dedicated power amplifiers required to drive it. Because this technology offers advantages of multi-channel RF field control, optimization, and efficiency, it would bring new advantages to 3T clinical imaging as well. Accordingly, a 3T clinical body coil system will be developed for commercial offering as well.

对于第二阶段 STTR 提案，研究人员计划开发射频 (RF) 并将其商业化 线圈技术使 7T 身体 MRI 成为可能，并将这项新技术转化为极大提高 3T 临床 MRI 也是如此。在导致该提案的第一阶段项目中，所有具体目标均已实现 首次展示了安全、成功地对人体进行成像的可行性 7T 的商用技术。该技术融合了多项创新，包括 自动调谐和匹配以及多通道发射射频场匀场。与全身线圈不同 这里开发的射频线圈技术内置于临床磁体的孔中，可以轻松改装到现有的 系统位于患者台顶部并紧密贴合身体以提高效率。二期工程 提议将提供该设备的改进的商业封装，带有内置的多通道专用 驱动它所需的功率放大器。因为该技术提供了多通道射频场的优势 控制、优化、效率，也将为3T临床影像带来新的优势。 因此，3T 临床身体线圈系统也将被开发用于商业供应。