MASS SPECTROMETRY OF GLYCOPROTEINS

糖蛋白的质谱分析

• 批准号: 8363036
• 负责人: Parastoo Azadi
• 金额: $ 0.34万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363036
• 关键词: Electrospray Ionization; Faculty; Funding; Glycoproteins; Grant; Lasers; Link; Manuals; Maps; Mass Spectrum Analysis; National Center for Research Resources; Oligosaccharides; Participant; Principal Investigator; Procedures; Research; Research Infrastructure; Resources; Site; Source; Techniques; Technology; United States National Institutes of Health; cost; glycosylation; instrument; lectures

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This is a two-day course with lectures by CCRC faculty and includes mapping the glycosylation sites in glycoproteins, determining the composition, sequencing, and branching points of N- and O-linked oligosaccharides, and MS procedures used in these analyses. Demonstrations are performed on both matrix-assisted laser desorption (MALDI) and electrospray ionization (ESI-MS) instruments. A course manual including selected analytical techniques and references is provided to each course participant.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 这是为期两天的CCRC教师讲座的课程，包括在糖蛋白中绘制糖基化位点，确定N-和O-链接的寡糖和MS过程的组成，测序和分支点。 示范是对基质辅助激光解吸（MALDI）和电喷雾电离（ESI-MS）仪器进行的。 提供了一本课程手册，包括选定的分析技术和参考文献。