OPTICAL BIOPSY OF HUMAN SKIN IN CONJUCTION WITH LASER TREATMENT

人体皮肤光学活检结合激光治疗

• 批准号: 8362609
• 负责人: ANTHONY J DURKIN
• 金额: $ 0.16万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362609
• 关键词: Aftercare; Biotechnology; Funding; Grant; Human; Image; Lasers; Measurement; National Center for Research Resources; Optical Biopsy; Optics; Principal Investigator; Property; Research; Research Infrastructure; Resources; Skin; Source; Techniques; United States National Institutes of Health; chromophore; cost; in vivo; interest; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this study is to quantify optical properties and chromophore concentrations for pre and post treatment skin and adjacent normal skin (in-vivo). Furthermore, in select cases, we will repeatedly perform measurements to record changes in post treatment skin and adjacent normal skin over a period of several weeks. Ultimately we are interested in developing a detailed understanding of the response of skin to therapy with the objective of optimizing therapy. Furthermore we will compare results obtained with SS-FDPM to those arrived at using Modulated Imaging in order to objectively assess the strengths and weaknesses of each technique.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 这项研究的目的是量化治疗后和邻近的正常皮肤（体内）的光学特性和发色团浓度。 此外，在某些情况下，我们将反复进行测量，以记录治疗后皮肤和邻近正常皮肤的变化。最终，我们有兴趣对皮肤对治疗的反应有详细的了解，以优化治疗。此外，我们将使用SS-FDPM获得的结果与使用调制成像到达的结果进行比较，以客观地评估每种技术的优势和劣势。