New Faculty Recruitment to Enhance Melanoma Research

招聘新教师以加强黑色素瘤研究

• 批准号: 7858928
• 负责人: STANTON L. GERSON
• 金额: $ 78.5万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7858928
• 关键词: Address; Administrative Supplement; Agreement; American; Antineoplastic Agents; Apoptotic; Applications Grants; Biological Markers; Biomedical Research; Cancer Center; Clinical Research; Clinical Trials; Collaborations; Communities; Comprehensive Cancer Center; DNA; Development; Disease; Economics; Employment; Etiology; Faculty; Fostering; Funding; Generations; Goals; Human Resources; Individual; Knowledge; Laboratories; Letters; Link; Mails; Malignant Neoplasms; Metabolism; Modeling; NCI Center for Cancer Research; National Cancer Institute; Newsletter; Notification; Occupations; Pathogenesis; Pathway interactions; Patients; Pilot Projects; Positioning Attribute; Reagent; Recovery; Research; Research Personnel; Resources; Signal Transduction; Staging; Technology; Therapeutic; Translational Research; Universities; angiogenesis; base; cancer therapy; drug development; medical schools; melanoma; member; novel; programs; public health relevance; ranpirnase; repaired; response; web site

DESCRIPTION (Provided by the applicant): In response to the National Cancer Institute American Recovery and Reinvestment Act (ARRA) Funded Administrative Supplements: Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers (P30), we propose a supplement to support the recruitment of early stage investigators and funding of pilot projects that will aid in the expansion of an initiative in melanoma disease focused basic and translational research at the Case Comprehensive Cancer Center. The melanoma disease team is a newer active collaborative group that is poised to grow into a major initiative within the Cancer Center. The recruitments described in this application will be critically important to the strengthening of the group and establishing a stronger cross-institutional program. We will benefit from a focused effort developing models of melanoma and are seeking highly collaborative individuals that will enhance our knowledge of the signaling mechanisms involved in melanoma development and progression as well as fund pilot projects in basic, translational and clinical research investigating the etiology, pathogenesis, and treatment of melanoma. Pilot grant applications will be solicited from members of the research community at Case Western Reserve University through Case CCC weekly newsletter, notification of all department chairs and center directors through letters and e-mail notices and notices through the School of Medicine and University newsletters. All application requirements will be available through the Case CCC web site. The RFA will state that these pilot projects are solicited to stimulate research that will expand our knowledge of melanoma, and generate and foster new and expanded collaborations to address the goals of the ARRA in multiple ways: 1) This application will provide employment for early stage investigators, research assistants and provide additional effort for research personnel, 2) will require the purchase of scientific materials and reagents, and 3) will result in new cancer treatments that will have a significant impact on patients. Generation of these therapeutics/technologies have also have a high potential for creating new jobs in the region, first by the use of funds for personnel in laboratories and later through formation of new start-up ventures or through support of commercial development via sponsored research agreements. Public Health Relevance: The faculty positions and pilot projects supported by this supplement will leverage existing research, stimulate further research, advance the research of the Cancer Center and Case Western Reserve University, and provide economic stimulation.

描述（由申请人提供）：为了响应国家癌症研究所美国复苏和再投资法案 (ARRA) 资助的行政补充：复苏法案有限竞争：支持新教师招聘以通过生物医学研究核心中心增强研究资源 (P30)，我们提出一项补充，以支持早期研究人员的招募和试点项目的资助，这将有助于扩大凯斯综合癌症中心以黑色素瘤疾病为重点的基础和转化研究计划。黑色素瘤疾病团队是一个较新的活跃协作小组，有望发展成为癌症中心内的一项重大举措。本申请中描述的招聘对于加强团队和建立更强大的跨机构计划至关重要。我们将受益于开发黑色素瘤模型的专注努力，并正在寻找高度协作的个人，以增强我们对黑色素瘤发展和进展所涉及的信号机制的了解，并资助基础、转化和临床方面的试点项目 调查黑色素瘤的病因、发病机制和治疗的研究。试点拨款申请将通过 Case CCC 每周通讯向凯斯西储大学研究界成员征求，通过信件和电子邮件通知所有系主任和中心主任，并通过医学院和大学通讯通知所有系主任和中心主任。所有申请要求均可通过 Case CCC 网站获取。 RFA 将声明，征集这些试点项目是为了刺激研究，扩大我们对黑色素瘤的了解，并产生和促进新的和扩大的合作，以多种方式实现 ARRA 的目标：1) 该应用程序将为早期阶段提供就业机会研究者、研究助理并为研究人员提供额外的努力，2）将需要购买科学材料和试剂，3）将产生对患者产生重大影响的新的癌症治疗方法。这些疗法/技术的产生也具有在该地区创造新就业机会的巨大潜力，首先通过为实验室人员使用资金，然后通过组建新的初创企业或通过赞助研究协议支持商业发展。 公共卫生相关性：本补充材料支持的教职职位和试点项目将利用现有研究，刺激进一步研究，推进癌症中心和凯斯西储大学的研究，并提供经济刺激。