CTRP Supplement

CTRP 补充

基本信息

批准号：
8765484
负责人：
STANTON L. GERSON
金额：
$ 3.7万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-04-01 至 2018-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8765484
关键词：
Achievement Advocate Basic Cancer Research Behavioral Biological Markers Cancer Center Cancer Center Support Grant Cancer Hospital Cancer Patient Cancer Research Infrastructure Caring Clinical Clinical Research Clinical Trials Clinics and Hospitals Collaborations Communities Community Outreach Comprehensive Cancer Center Detection Diagnosis Disease Education Family Focus Groups Funding Grant Health system Human Institution Instruction Intervention Laboratories Leadership Link Malignant Neoplasms Medical Research Mission Morbidity - disease rate Newly Diagnosed Ohio Outcome Patients Population Population Research Prevention Preventive Intervention Research Research Infrastructure Research Peer Review Research Personnel Research Support Resource Development Resource Sharing Risk Schools Scientist Speed Strategic Planning Testing Therapeutic Training Programs Translational Research Translations Universities University Hospitals anticancer research bench to bedside cancer care cancer initiation cancer prevention cancer therapy clinical application improved innovation investigator-initiated translational research medical schools meetings member multidisciplinary new therapeutic target outcome forecast patient population programs survivorship tumor progression

项目摘要

DESCRIPTION (provided by applicant): The mission of Case Comprehensive Cancer Center (Case CCC), now in its 25th year of NCI designation, is to promote a coordinated, translational research-oriented culture of scientific discovery applied to human cancers, with dissemination to patients and populations to improve cancer prevention, detection, treatment, cure, and survivorship. The Center provides leadership and oversight of collaboration for basic cancer research oriented toward identification of novel therapeutic targets; prevention, control and population research; therapeutic and non-therapeutic clinical research across the disease spectrum; and community outreach. The Center coordinates all aspects of cancer research in Cleveland and Northern Ohio, including activities of the affiliate institutions of Case Western Reserve University School of Medicine: Cleveland Clinic and University Hospitals. The Center provides opportunities to participate in clinical trials to almost 10,000 cancer patients who are newly diagnosed annually in the region. The opening in 2011 of the new freestanding cancer hospital, UH Seidman Cancer Center, and the funding of the Gl SPORE represent major achievements in this past grant cycle. The Case CCC is organized around 8 Scientific Programs, 15 shared resources, and a clinical and behavioral cancer research infrastructure that prioritizes innovative translational research and investigator-initiated clinical trials that ut across the Scientific Programs. The Case CCC includes 232 full members (335 total members) from 5 schools and 30 academic departments who actively participate in Cancer Center activities including Program and Core meetings and retreats, leadership committees, and scientific focus groups, each promoting a transdisciplinary approach that facilitates discovery and clinical application. The Cancer focus of the Center is exceptional, with over $116M in total funding and over $45M in total NCI funding. Institutional commitment is also exceptional with over $115M dedicated to cancer research in the next cycle and over $350M in construction anticipated. The Case CCC and its affiliate institutions have established an outstanding infrastructure that enables its members to improve the prevention, diagnosis, and treatment of cancer through discovery, implementation and dissemination, while providing state-of-the-art care and treatment to cancer patients and their families. The Case CCC is a significant partner with the NCI in its effort to change the practice of cancer care through discovery and clinical research of the highest quality.

描述（由申请人提供）：凯斯综合癌症中心 (Case CCC) 现已进入 NCI 指定第 25 个年头，其使命是促进协调一致、以转化研究为导向的科学发现文化应用于人类癌症，并将其传播到患者和人群改善癌症的预防、检测、治疗、治愈和生存。该中心为基础癌症研究的合作提供领导和监督，旨在确定新的治疗靶点；预防、控制和人口研究；跨疾病谱的治疗性和非治疗性临床研究；和社区外展。该中心协调克利夫兰和俄亥俄州北部癌症研究的各个方面，包括凯斯西储大学医学院附属机构：克利夫兰诊所和大学医院的活动。该中心每年为该地区近万名新诊断的癌症患者提供参与临床试验的机会。 2011 年新的独立癌症医院 UH Seidman 癌症中心的开业以及 GL SPORE 的资助代表了上一个资助周期的重大成就。 Case CCC 围绕 8 个科学计划、15 个共享资源以及临床和行为癌症研究基础设施进行组织，该基础设施优先考虑跨科学计划的创新转化研究和研究者发起的临床试验。案例 CCC 包括来自 5 所学校和 30 个学术部门的 232 名正式成员（总共 335 名成员），他们积极参与癌症中心的活动，包括计划和核心会议和务虚会、领导委员会和科学焦点小组，每个成员都提倡采用跨学科方法，促进发现及临床应用。该中心的癌症重点非常突出，总资金超过 1.16 亿美元，NCI 总资金超过 4500 万美元。机构承诺也非常出色，下一个周期将有超过 1.15 亿美元专门用于癌症研究，预计建设将超过 3.5 亿美元。 Case CCC 及其附属机构建立了出色的基础设施，使其成员能够通过发现、实施和传播来改善癌症的预防、诊断和治疗，同时为癌症患者和患者提供最先进的护理和治疗。他们的家人。 Case CCC 是 NCI 的重要合作伙伴，NCI 致力于通过最高质量的发现和临床研究来改变癌症护理实践。