Novel MRI Gradient Coil Manufacturing Methods

新型 MRI 梯度线圈制造方法

基本信息

批准号：
8312984
负责人：
Irving Weinberg
金额：
$ 34.02万
依托单位：
WEINBERG MEDICAL PHYSICS, LLC
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-01 至 2014-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8312984
关键词：
3-Dimensional Algorithms Amplifiers Animals Businesses Capital Clinical Computer software Elongation Factor Equipment Fiber Fractals Frequencies Future Goals Grant Head Heating Human Image Ink Intellectual Property Investments Lead Licensing Magnetic Resonance Imaging Manufacturer Name Marketing Medical Medical Imaging Methods Modeling Morphologic artifacts Nanotechnology National Center for Research Resources Performance Phase Physiologic pulse Price Printing Process Property Recycling Research Resistance Site Small Business Innovation Research Grant Study Section System Techniques Technology Temperature Tensile Strength Thick Time base clinical research site commercialization computer generated cost design flexibility improved innovation instrumentation interest magnetic field manufacturing process mathematical algorithm meetings millisecond nano nanosilver novel operation pre-clinical prototype satisfaction success symposium voltage

项目摘要

DESCRIPTION (provided by applicant): We aim to improve the performance of pre-clinical and clinical MRI systems, while reducing manufacturing costs. These aims will be achieved by replacing existing wire- based gradient coil construction methods with novel proprietary 3-D additive manufacturing techniques. 3-D printing of conductive nano-inks and of insulating layers (according to computer- generated designs) is a natural way to implement mathematical algorithms developed to optimize magnetic field coil configurations. We have already performed proof-of- principle studies showing that our mesoscale coil manufacturing techniques result in reduced resistance at high frequencies, a goal previously accomplished only with time- consuming processes involving the wrapping of expensive Litz wires. By including sacrificial materials into the additive manufacturing process, we have incorporated fractal branching channels for circulating coolant materials within the coil geometry. This innovation promises to significantly improve heat transfer. In Phase I, we will adapt gradient design algorithms to the additive manufacturing process, and build and characterize a prototype gradient coil. In cooperation with a strategic partner already well-established in the MRI field, we will prepare for Phase II by offering a design for a future human head-coil based on the novel manufacturing technology. PUBLIC HEALTH RELEVANCE: We aim to improve the performance of pre-clinical and clinical MRI systems, while reducing manufacturing costs. These aims will be achieved by replacing existing wire-based gradient coil construction methods with novel proprietary 3-D additive manufacturing techniques. In Phase I, we will adapt gradient design algorithms to the additive manufacturing process, and build and characterize a prototype gradient coil. In cooperation with a strategic partner already well- established in the MRI field, we will prepare for Phase II by offering a design of a human head- coil based on the novel manufacturing technology.

描述（由申请人提供）：我们旨在提高临床前和临床MRI系统的性能，同时降低制造成本。这些目标将通过用新型专有3-D增材制造技术代替现有的基于电线的梯度线圈构造方法来实现这些目标。 3-D打印导电纳米键和绝缘层（根据计算机生成的设计）是实现用于优化磁场线圈配置的数学算法的自然方法。我们已经进行了原则证明研究，表明我们的中尺度线圈制造技术在高频下导致电阻降低，这一目标以前只有在涉及包装昂贵的LITZ电线包装的时间消耗过程中才实现的目标。通过将牺牲材料包括在添加剂制造过程中，我们将循环冷却液材料的分形分支通道纳入了线圈几何形状。这项创新有望显着改善传热。在第一阶段，我们将将梯度设计算法调整为添加剂制造过程，并构建和表征原型梯度线圈。与已经在MRI领域建立了良好的战略合作伙伴合作，我们将为 II阶段通过为新型制造技术提供设计的设计设计。公共卫生相关性：我们旨在提高临床前和临床MRI系统的性能，同时降低制造成本。这些目标将通过使用新型专有的3-D增材制造技术代替现有的基于电线的梯度线圈构造方法来实现这些目标。在第一阶段，我们将将梯度设计算法调整为添加剂制造过程，并构建和表征原型梯度线圈。在与已经在MRI领域建立的战略合作伙伴合作，我们将通过基于新型制造技术的设计人体设计来为II期准备。