CC: Biostatistics and Bioinformatics Core

CC：生物统计学和生物信息学核心

• 批准号: 8321877
• 负责人: Edie A Weller
• 金额: $ 12.64万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8321877
• 关键词: Applications Grants; Bioinformatics; Biometry; Characteristics; Clinical Protocols; Clinical Research; Clinical Trials; Collaborations; Computers; Consult; Consultations; Data; Data Analyses; Data Collection; Data Quality; Databases; Development; Education; Epidemiologic Studies; Genomics; Goals; Laboratories; Laboratory Animals; Manuscripts; Mentors; Methods; Multiple Myeloma; Outcome; Patients; Preparation; Procedures; Process; Quality Control; Recommendation; Reporting; Research Personnel; Research Project Grants; Specialist; career development; computer infrastructure; computerized data processing; data management; design; experience; high throughput analysis; member; quality assurance; research study; success

The purpose of this core is to provide the following functions that will be utilized by the research projects and the clinical studies in the SPORE: Specific Aim 1. To provide biostatistical collaboration for SPORE Projects, Developmental Projects and Cores. This includes all aspects of design, conduct, analysis and reporting of laboratory and clinical protocols; including the coordination of laboratory results with patient characteristics and outcomes from the clinical studies. Specific Aim 2. To provide consulting and statistical education to SPORE researchers. Specific Aim 3. To provide or recommend supporting computational infrastructure. This includes collaboration with the multiple myeloma clinical research coordinators (CRC) and the data specialist at the Quality Assurance Office for Clinical Trials (QACT) on the collection of data, forms development, data processing and quality assurance of clinical trials data, as well as consultation on computer databases, moving data between data bases for laboratory, animal and relevant clinical studies Specific Aim 4. To provide bioinformatic support for analysis of high throughput transcriptional and genomic studies.

该核心的目的是提供以下功能，供 SPORE 的研究项目和临床研究： 具体目标 1. 为 SPORE 项目、发展项目和 核心。这包括实验室和临床的设计、实施、分析和报告的所有方面 协议；包括实验室结果与患者特征和结果的协调 临床研究。 具体目标 2. 为 SPORE 研究人员提供咨询和统计教育。 具体目标 3. 提供或推荐支持性计算基础设施。这包括 与多发性骨髓瘤临床研究协调员 (CRC) 和数据专家合作 临床试验质量保证办公室 (QACT) 关于数据收集、表格开发、数据 临床试验数据的处理和质量保证，以及计算机数据库的咨询， 在实验室、动物和相关临床研究的数据库之间移动数据 具体目标4.为高通量转录和基因组分析提供生物信息学支持 研究。