CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365037
• 负责人: Barry Coller
• 金额: $ 112.75万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365037
• 关键词: Acquired Immunodeficiency Syndrome; Health; Human; Research; Research Infrastructure; Translational Research; science education

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The goal of The Rockefeller University Center for Clinical and Translational Science is to improve human health by: 1. providing an infrastructure to conduct clinical investigation at the highest level, educational programs to train future generations of skilled and committed investigators, and novel methods of clinical investigation that can be shared with others, and 2. working closely with other CTSA institutions to set national standards so as to improve the conduct of clinical research. The 2006 Clinical and Translational Science Award transformed translational research at Rockefeller University and we propose to build on these accomplishments by: 1) enhancing our KL2 Master's degree and Certificate in Clinical and Translational Science educational programs; 2) creating a new educational program for our current K08 and K23 awardees to speed their transition to scientific independence; 3) expanding our bidirectional community engaged research with our partner institutions, integrating molecular mechanistic and population-based components, 4) completing the implementation of our integrated, customized information technology infrastructure to facilitate protocol development, review, and conduct; 5) implementing a novel real-time monitoring system to insure compliance with Good Clinical Practice; 6) enhancing our multi-disciplinary and multi-departmental Protocol Navigation program to speed protocol development, approval, and implementation, and extending it to bidirectional community engaged research; 7) expanding the application of novel nonparametric biostatistical methods to genomic and community-based investigation; 8) utilizing our new deep human phenotyping systems to aid scientific discovery and address important clinical needs; 9) utilizing a validated measure of research participants' perceptions to improve the conduct of clinical research; and 10) continuing to actively participate in the national CTSA consortium to advance the discipline of clinical and translational science for the benefit of human health. PUBLIC HEALTH RELEVANCE (provided by applicant): The Rockefeller University Center for Clinical and Translational Science is dedicated to improving human health by providing the resources and personnel to conduct the highest quality research to improve the prevention, diagnosis, and treatment of human disease. It also is producing novel methods to improve the scientific information obtained from clinical research studies and the way in which the research is performed.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 描述（由申请人提供）：洛克菲勒大学临床和转化科学中心的目标是改善人类健康，作者：1。提供基础架构，在最高级别进行临床调查，教育计划，教育计划，以培训未来的熟练和实施的研究人员，并与其他临床进行临床的临床标准，以及与其他临床的临床标准，以及与其他临床进行的临床，以及与其他临床的共享。 研究。 2006年的临床和转化科学奖改变了洛克菲勒大学的翻译研究，我们建议通过以下方面的成就来建立这些成就：1）增强我们的KL2硕士学位和临床和转化科学教育计划的KL2硕士学位和证书； 2）为当前的K08和K23获奖者创建一个新的教育计划，以加快其向科学独立性的过渡； 3）扩大双向社区与合作伙伴机构进行研究，整合分子机械和基于人群的组件，4）完成我们综合，定制的信息技术基础设施的实施，以促进协议开发，审查和行为； 5）实施一种新型的实时监测系统，以确保符合良好的临床实践； 6）加强我们的多学科和多部门协议导航计划，以加快协议开发，批准和实施，并将其扩展到双向社区参与研究； 7）扩大新型非参数生物统计学方法在基因组和社区研究中的应用； 8）利用我们新的深人类表型系统来帮助科学发现并满足重要的临床需求； 9）利用验证的研究参与者的看法来改善临床研究的行为； 10）继续积极参与国家CTSA财团，以促进临床和转化科学的纪律，以造福人类健康。 公共卫生相关性（由申请人提供）：洛克菲勒大学临床与转化科学中心致力于通过提供资源和人员来进行最高质量的研究来改善人类疾病的预防，诊断和治疗，从而改善人类健康。它还正在生产新的方法，以改善从临床研究中获得的科学信息以及进行研究的方式。