Center for the Study of Reproductive Biology and Women's Health

生殖生物学与妇女健康研究中心

• 批准号: 8247651
• 负责人: JEFFREY W. POLLARD
• 金额: $ 136.07万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-03 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8247651
• 关键词: Appointment; Basic Science; Cell Proliferation; Clinical; Competence; Endometrial; Estrogens; Faculty; Fellowship; Female; Funding; Hormonal; Human; Individual; Infertility; Institution; Insulin-Like Growth Factor I; Leptin; Medicine; Neurosecretory Systems; Obesity; Principal Investigator; Progesterone; Publishing; Regulation; Reproduction; Reproductive Biology; Research; Research Personnel; Role; Training; Women' s Health; Work; college; meetings; nutrition; programs; reproductive; reproductive function; symposium

DESCRIPTION (provided by applicant): The proposed Specialized Cooperative Center Program in Reproductive and Infertility Research (SCCPIR) is focused upon female reproductive biology with Dr. Jeffrey W. Pollard as Principal Investigator. It has evolved out of an institutional supported "Center for the Study of Reproductive Biology and Women's Health" founded in 2003 at the Albert Einstein College of Medicine with Dr. Pollard as Director. This Center drew together disparate strands of research in the female reproduction at the institution to form a distinct group of interactive individuals who have a translational focus. Investigators with this Center have worked for the last four years to develop this submission and in doing so have met regularly to undertake collaborative projects and used institutional funds to support clinical fellowship training relevant to the study of female reproduction. In doing so the PI's of the proposed projects have all published with one another and they have identified several fellows to be brought onto faculty to perform clinical/basic science research. The SCCPIR has four Projects (Projects 1 and 2 being clinical) and an administrative core as follows: Project 1. Dr. Jeffrey Pollard (PI) - Estrogen and Progesterone Regulation of Human Endometrial Cell Proliferation. Project 2. Dr. Nanette Santoro (PI) - Reproductive hormonal alterations in obesity. Project 3. Dr. Anne Etgen (PI) - IGF-I and Neuroendocrine Regulation of Female Reproductive Function. Project 4. Dr. Streamson Chua (PI) - Antagonistic actions of melanocortins and leptin on reproductive competence. A senior investigator leads all of these projects. There is integration amongst the projects through studies on the roles of obesity and nutrition in reproductive biology as well as the relationship between the insulin-like growth factor-1 axis and estrogen action. The PI, Dr. Jeffrey W. Pollard, is an internationally known researcher in reproductive biology having been, amongst other things, Chair of the Reproductive Tract Gordon Conference. He holds several senior administrative appointments in the College of Medicine and is well able to administer the proposed SCCPIR internally and to enable effective interactions with other SCCPIRs.

描述（由申请人提供）：拟议的生殖和不育研究专业合作中心计划（SCCPIR）侧重于女性生殖生物学，杰弗里·W·波拉德（Jeffrey W. Pollard）博士担任首席研究员。它是由机构支持的“生殖生物学和妇女健康研究中心”演变而来的，该中心于2003年在阿尔伯特·爱因斯坦医学院与Pollard博士担任董事。该中心在机构的女性繁殖中汇集了不同的研究研究，形成了具有转化重点的独特互动个体。该中心的调查人员在过去四年中一直在努力开发此提交，并经常开会开展协作项目，并利用机构资金来支持与女性繁殖研究有关的临床奖学金培训。在这样做的过程中，拟议项目的PI彼此发表了，他们已经确定了几个研究员将被带到教职员工上，以进行临床/基础科学研究。 Sccpir有四个项目（项目1和2是临床），一个行政核心如下： 项目1。JeffreyPollard博士（PI） - 人子宫内膜细胞增殖的雌激素和孕酮调节。 项目2。NanetteSantoro博士（PI） - 肥胖症的生殖激素改变。 项目3。AnneEtgen博士（PI） - 女性生殖功能的IGF -I和神经内分泌调节。 项目4。PreamsonChua博士（PI） - 黑色素皮质和瘦素对生殖能力的拮抗作用。 一名高级调查员领导所有这些项目。通过研究肥胖和营养在生殖生物学中的作用以及胰岛素样生长因子-1轴与雌激素作用之间的关系，项目之间存在整合。 PI，Jeffrey W. Pollard博士是一位国际知名的生殖生物学研究员，除其他外，还曾是殖民地戈登会议的主席。他在医学院任职几个高级行政任命，并且能够内部管理拟议的Sccpir，并有效与其他Sccpir进行有效互动。