Center for the Study of Reproductive Biology and Women's Health

生殖生物学与妇女健康研究中心

• 批准号: 8063413
• 负责人: JEFFREY W. POLLARD
• 金额: $ 3.98万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-15 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8063413
• 关键词: Address; Aging; American; Appointment; Award; Basic Science; Cell Proliferation; Clinical; Communities; Competence; Doctor of Philosophy; Endometrial; Estrogens; Faculty; Fellowship; Female; Foundations; Funding; Future; Grant; Gynecologist; Hormonal; Human; Individual; Infertility; Institution; Institutional National Research Service Award; Insulin-Like Growth Factor I; Joints; K-Series Research Career Programs; Laboratories; Leptin; Medicine; Mission; NCI Scholars Program; Neurosecretory Systems; Obesity; Pennsylvania; Physicians; Positioning Attribute; Principal Investigator; Progesterone; Program Development; Publishing; Regulation; Reproduction; Reproductive Biology; Reproductive Endocrinology; Reproductive Medicine; Research; Research Personnel; Role; SECTM1 gene; Science; Scientist; Training; Training Programs; Translational Research; Travel; Universities; Wages; Women' s Health; Work; college; meetings; member; nutrition; professor; programs; reproductive; reproductive function; symposium

The proposed Specialized Cooperative Center Program in Reproductive and Infertility Research (SCCPIR) is focused upon female reproductive biology with Dr. Jeffrey W. Pollard as Principal Investigator. It has evolved out of an institutional supported "Center for the Study of Reproductive Biology and Women's Health" founded in 2003 at the Albert Einstein College of Medicine with Dr. Pollard as Director. This Center drew together disparate strands of research in the female reproduction at the institution to form a distinct group of interactive individuals who have a translational focus. Investigators with this Center have worked for the last four years to develop this submission and in doing so have met regularly to undertake collaborative projects and used institutional funds to support clinical fellowship training relevant to the study of female reproduction. In doing so the Pi's of the proposed projects have all published with on another and they have identified several fellows to be brought onto faculty to perform clinical/basic science research. The SCCPIR has four Projects (Projects 1 and 2 being clinical) and an administrative core as follows: Project 1. Dr. Jeffrey Pollard (PI) Estrogen and Progesterone Regulation of Human Endometrial Cell Proliferation. Project 2. Dr. Nanette Santoro (PI) Reproductive hormonal alterations in obesity. Project 3. Dr. Anne Etgen (PI) IGF-I and Neuroendocrine Regulation of Female Reproductive Function. Project 4. Dr. Streamson Chua (PI) Antagonistic actions of melanocortins and leptin on reproductive competence. A senior investigator leads all these projects. There is integration amongst the projects through studies on the roles of obesity and nutrition in reproductive biology as well as the relationship between the insulin-like growth factor-1 axis and estrogen action. The PI, Dr. Jeffrey W. Pollard, is an internationally known researcher in reproductive biology having been amongst other things Chair of the Reproductive Tract Gordon Conference. He holds several senior administrative appointments in the College of Medicine and is well able to administer the proposed SCCPIR internally and to enable effective interactions with other SCCPIRs.

拟议的专业合作中心在生殖和不育研究（SCCPIR）方面侧重于女性生殖生物学，Jeffrey W. Pollard博士担任首席研究员。它已经从机构支持的“生殖生物学研究中心和妇女的研究中心进化出来 卫生”“ 2003年在阿尔伯特·爱因斯坦医学院（Albert Einstein Medicine of Pollard）担任董事。该中心在该机构的女性繁殖中汇集了不同的研究，形成了一个独特的互动人群，这些人具有翻译重点。 在过去的四年中，要开发这一提交，并经常开会开展协作项目，并利用机构资金来支持与女性繁殖研究有关的临床奖学金培训。为此，拟议项目的PI都与另一个项目一起发表，他们已经确定了几个研究员将被带到教师身上，以进行临床/基础科学研究。 Sccpir有四个项目（项目1和2是临床），一个行政核心如下： 项目1。杰弗里·波拉德（Jeffrey Pollard）博士（PI）雌激素和孕激素对人子宫内膜细胞增殖的调节。 项目2。NanetteSantoro博士（PI）肥胖症的生殖激素改变。 项目3。女性生殖功能的Anne Etgen博士（PI）IGF-I和神经内分泌调节。 项目4。黑色素皮质和瘦素的Streamson Chua（PI）拮抗作用 关于生殖能力。 一名高级调查员领导所有这些项目。通过研究肥胖和营养在生殖生物学中的作用以及胰岛素样生长因子-1轴与雌激素作用之间的关系，项目之间存在整合。 PI，Jeffrey W. Pollard博士是一位国际知名的生殖生物学研究人员，曾是戈登殖民地戈登会议的其他主席。他在医学院任职几个高级行政任命，并且能够内部管理拟议的Sccpir，并有效与其他Sccpir进行有效互动。