Diagnosis of Crystal-Based Arthropathies via Raman Spectroscopy

通过拉曼光谱诊断晶体关节病

• 批准号: 8322612
• 负责人: Ozan Akkus
• 金额: $ 33.96万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8322612
• 关键词: Adoption; Affect; Aliquot; Arthritis; Aspirate substance; Biomedical Engineering; Calcium Oxalate; Calcium Pyrophosphate; Calcium Pyrophosphate Dihydrate; Chemicals; Clinic; Clinical; Collaborations; Collection; Communities; Complex; Cost Savings; Cystine; Data; Decision Making; Deposition; Deterioration; Devices; Diagnosis; Diagnostic Procedure; Disease; Engineering; Evaluation; Facilities and Administrative Costs; Fever; Filtration; Foundations; Goals; Gold; Gout; Head; Health system; Home environment; Hospitals; Image; Impairment; Inflammatory; Investigation; Joints; Kidney; Lasers; Lead; Letters; Light; Location; Maps; Medical; Methods; Microscope; Microscopic; Modality; Morbidity - disease rate; Pain; Pathology; Patients; Perception; Pharmaceutical Preparations; Photons; Physicians; Preparation; Prevalence; Primary Health Care; Process; Pseudogout; Quality Control; Quality of life; Raman Spectrum Analysis; Reaction; Research; Resort; Resources; Rheumatology; Roentgen Rays; Sampling; Screening procedure; Sensitivity and Specificity; Serum; Signal Transduction; Spottings; Swelling; Symptoms; Syringes; Techniques; Technology; Time; Training; Translating; Urate; Validation; Work; Xanthines; arthropathies; base; calcium phosphate; clinical Diagnosis; clinical practice; clinically relevant; cost; cost effective; improved; instrument; medical specialties; millimeter; novel; patient population; point of care; polarized light; primary care setting; programs; prototype; rheumatologist; tool; user-friendly

DESCRIPTION (provided by applicant): The overall goal of the proposed study is to assess the efficiency of diagnosing crystals leading to inflammation of joints using a cost-efficient device which uses laser light. The study will fabricate the device, collect samples from the clinic and determine the sensitivity of the method in comparison to existing clinical diagnostic methods.

描述（由申请人提供）：拟议研究的总体目标是评估使用具有成本效益的激光设备诊断导致关节炎症的晶体的效率。该研究将制造该设备，从诊所收集样本，并与现有的临床诊断方法相比确定该方法的灵敏度。