Centers for AIDS Research (CFAR)

艾滋病研究中心 (CFAR)

• 批准号: 8105503
• 负责人: Kent J. Weinhold
• 金额: $ 212.79万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-15 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8105503
• 关键词: Centers; AIDS; Research; CFAR

DESCRIPTION (provided by applicant): The principal mission of the Duke Center for AIDS Research (CFAR) is to promote the collaboration and coordination of AIDS-related research by supporting the scientific needs of the basic and clinical HIV/AIDS research community at Duke. In this competitive renewal application, the new Duke CFAR seeks to use its newly established leadership role within the Medical Center to build upon the many important accomplishments of its first 4 years in existence and, in doing so, to further expand the overall infrastructure and programmatic support that will continue to provide cost effective state of the art essential services while also serving as a catalyst for future HIV/AIDS collaborative research initiatives at Duke. The highly successful Small Grant support mechanism as well as the active recruitment of 5 new key HIV/AIDS investigators to Duke both form a solid basis in moving forward into the next funding cycle. Through a highly effective Strategic Planning process, the Duke CFAR leadership, in consultation with the Duke CFAR External Advisory Committee has identified 4 priority areas for development and support over the next 5 years, that comprise the Specific Aims for this proposal and include 1) creation of an AIDS-associated malignancies basic and clinical research program at Duke in collaboration with the Duke Comprehensive Cancer Institute (DCCI), 2) development and support of a comprehensive clinical database and linked specimen repository, 3) programmatic focus on HIV pathogenesis and elimination of viral reservoirs through targeted RFAs and faculty recruitment support, and 4) full engagement of the human genomics leadership on campus through integration with the Duke CFAR. The joint CFAR-DCCI initiative for Aim 1 is further substantiated by philanthropic matching funds made available by the DCCI Director. During the initial year of new funding, the Duke CFAR service Cores will begin operating as 'partial' shared resources supported by discounted service fees and reduced CFAR investment, thus freeing funds for use in further expansion of the CFAR Cores and services as emerging needs and opportunities arise. In addition to its overall infrastructure support, the new Duke CFAR is now firmly entrenched in a highly-recognized leadership position at Duke and occupies an all important 'seat at the table' in the critical decision-making processes within the Medical Center. The CFAR leadership looks forward to providing enhanced services and support to the Duke HIV/AIDS research community in conjunction with the next 5 years of NIH funding.

描述（由申请人提供）：杜克大学艾滋病研究中心 (CFAR) 的主要使命是通过支持杜克大学基础和临床艾滋病毒/艾滋病研究界的科学需求，促进艾滋病相关研究的合作和协调。在这一竞争性的更新申请中，新的杜克 CFAR 寻求利用其在医疗中心内新确立的领导作用，在其成立前 4 年取得的许多重要成就的基础上再接再厉，并在此过程中进一步扩展整体基础设施和计划支持将继续提供具有成本效益的最先进的基本服务，同时也成为杜克大学未来艾滋病毒/艾滋病合作研究计划的催化剂。非常成功的小额资助支持机制以及杜克大学积极招募 5 名新的艾滋病毒/艾滋病关键研究人员，都为进入下一个资助周期奠定了坚实的基础。通过高效的战略规划流程，杜克大学 CFAR 领导层与杜克大学 CFAR 外部咨询委员会协商，确定了未来 5 年内发展和支持的 4 个优先领域，其中包括本提案的具体目标，包括 1) 创建杜克大学与杜克大学综合癌症研究所 (DCCI) 合作开展艾滋病相关恶性肿瘤基础和临床研究项目，2) 开发和支持综合临床数据库和链接样本库，3) 重点关注艾滋病毒发病机制和消除艾滋病毒通过有针对性的 RFA 和教师招聘支持来建立病毒库，4) 通过与杜克大学 CFAR 整合，让校园内人类基因组学领导层充分参与。 DCCI 主任提供的慈善配套资金进一步证实了针对目标 1 的 CFAR-DCCI 联合倡议。在新资金的第一年，杜克 CFAR 服务核心将开始作为“部分”共享资源运行，并得到折扣服务费和减少 CFAR 投资的支持，从而释放资金，用于根据新需求和服务进一步扩展 CFAR 核心和服务。机会出现。除了整体基础设施支持外，新的杜克 CFAR 现在在杜克大学牢牢占据了高度认可的领导地位，并在医疗中心的关键决策过程中占据了非常重要的“席位”。 CFAR 领导层期待结合 NIH 未来 5 年的资助，为杜克大学艾滋病毒/艾滋病研究界提供增强的服务和支持。