ANIMAL MODELS CORE

动物模型核心

基本信息

批准号：
8378204
负责人：
Fiona Claire Hankenson
金额：
$ 21.97万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8378204
关键词：
Accreditation Adenoviruses Am 80 Animal Model Animals Area Arts Autopsy Basic Science Biological Breeding Budgets Cardiovascular Diseases Censuses Clinical Containment Containment of Biohazards DNA Viruses Development Diagnostic radiologic examination Enrollment Evaluation Faculty Gene Transfer Glass Goals Head Housing IACUC Individual Laboratory Animal Medicine Laboratory Animals Life Location Macaca Macaca mulatta Maintenance Mission Monkeys Mus Operative Surgical Procedures Oryctolagus cuniculus Papio Pennsylvania Phase Primates Principal Investigator Procedures Protocols documentation Recombinants Regulatory Affairs Reporting Research Research Design Research Infrastructure Rodent Safety Sampling Services Therapeutic Studies Translational Research Universities Vaccines Veterinarians Viral Vector Work animal facility animal resource cost gene therapy in vivo interest nonhuman primate novel operation pre-clinical professor programs research study square foot vector

项目摘要

The Gene Therapy Program has access to animal facilities of importance to this P01. Dr. Wilson has managed mouse and nonhuman primate vivaria at Penn for the last 14 years. These facilities are stateof- the-art, are operated under BSL2 and are AAALAC accredited. The University Laboratory Animal Resources (ULAR) provides clinical veterinarian support to both vivaria. The nonhuman primate facility is dedicated to Dr. Wilson's use, while the mouse vivarium was developed for the use of those faculty involved in gene therapy research. Dr. Claire Hankenson, (Assistant Professor of Laboratory Animal Medicine, Dept of Pathobiology and Senior Associate Director for Regulatory Affairs and Planning, ULAR) will serve as Director of the Core. The mouse oncogenicity study will be performed in a dedicated room within the mouse facility. All nonhuman primate experiments will be implemented by the Core with biological samples being provided to the Projects and other Cores. The Core will also provide support for all mouse procedures and maintenance of all breeding colonies.

该基因治疗计划可以使用该P01重要性的动物设施。威尔逊博士有在过去的14年中，宾夕法尼亚州托管老鼠和非人类的Primate Vivaria。这些设施是 The-Art是根据BSL2操作的，并获得了AAALAC的认可。大学实验室动物资源（ULAR）为两个Vivaria提供临床兽医支持。非人类灵长类设施专门用于威尔逊博士的使用，而鼠标是用于使用这些教师的参与基因治疗研究。克莱尔·汉克森（Claire Hankenson）博士（实验室动物助理教授医学，病理生物学系，监管事务和规划高级副主任， Ular）将担任核心主任。小鼠致癌性研究将在鼠标设施内的专用房间。所有非人类灵长类动物实验将由将生物样品提供给项目和其他核心的核心。核心也将提供支持所有小鼠程序和所有育种菌落的维护。