54th Annual Thomas L. Petty Aspen Lung Conference: COPD and Lung Cancer: Common P

第 54 届 Thomas L. Petty Aspen 肺病年度会议：慢性阻塞性肺病和肺癌：常见 P

• 批准号: 8129411
• 负责人: Rubin M. Tuder
• 金额: $ 1.5万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129411
• 关键词: Address; Area; Basic Science; Boston; Chronic Obstructive Airway Disease; Clinical; Clinical Research; Clinical Sciences; Critical Care; Disease; Doctor of Medicine; Epidemic; Epigenetic Process; Event; Gene Mutation; Genetic Predisposition to Disease; Hospitals; Inflammation; Institutes; International; Joints; Knowledge; Lung; Lung diseases; Malignant neoplasm of lung; Medicine; National Heart, Lung, and Blood Institute; Participant; Pathogenesis; Preventive Intervention; Research; Research Personnel; Role; Science; Time; Translational Research; United States National Institutes of Health; Universities; Woman; cigarette smoking; falls; genetic epidemiology; novel; professor; programs; respiratory; senescence; stem cell biology; symposium

DESCRIPTION (provided by applicant): The theme of the 54th Annual Thomas L. Petty Aspen Lung Conference is "COPD and Lung Cancer: Common Pathogenesis Shared Clinical Challenges". The emphasis will be on the integration of basic, translational and clinical sciences. The clinical impact of COPD and lung cancer, the most frequent complications related to the cigarette smoke epidemic will be explored, and the program will identify shared and unique mechanistic events in each disease's pathogenesis Anchored by twelve "state-of-the-art" presentations, thematic sessions will address in both disorders genetic susceptibility and epidemiology, respiratory stem cell biology, role of senescence, genetic mutations, epigenetics, systemic inflammation, novel targeted therapies, and disease modifying or preventive interventions. This focus is in line with the recent joint effort by the NHLBI and NCI to address the mechanism underlying both COPD and lung cancer. The Conference Summary will be presented by Bartolome Celli, M.D., Professor of Medicine, Harvard University, Division of Pulmonary Sciences and Critical Care Medicine, Brigham and Women's Hospital, Boston. The main objectives of the conference are to 1) provide an international forum for basic and clinical researchers to exchange ideas relating to two major interrelated lung diseases; 2) fill a recognized need for participation in a field where knowledge is doubling every five years; 3) provide an opportunity for participants to focus in depth on a single topic by review and discussion with nationally and internationally recognized clinicians and researchers; and 4) provide an impetus to further research in pulmonary and critical care medicine

描述（由申请人提供）：第 54 届 Thomas L. Petty Aspen 肺部会议的主题是“慢性阻塞性肺病和肺癌：共同的发病机制、共同的临床挑战”。重点将放在基础科学、转化科学和临床科学的整合上。将探讨慢性阻塞性肺病和肺癌的临床影响、与香烟烟雾流行相关的最常见并发症，并且该计划将确定每种疾病发病机制中共同和独特的机制事件，以十二个“最先进”的演示为基础专题会议将讨论两种疾病的遗传易感性和流行病学、呼吸干细胞生物学、衰老的作用、基因突变、表观遗传学、全身炎症、新型靶向疗法以及疾病改变或预防干预措施。这一重点与 NHLBI 和 NCI 最近共同努力解决 COPD 和肺癌的潜在机制是一致的。会议摘要将由哈佛大学波士顿布莱根妇女医院肺科学和重症监护医学部医学教授 Bartolome Celli 医学博士发表。会议的主要目标是：1）为基础和临床研究人员提供一个国际论坛，以交流有关两种主要相互关联的肺部疾病的想法； 2）满足参与知识每五年翻一番的领域的公认需求； 3) 通过与国内和国际认可的临床医生和研究人员进行回顾和讨论，为参与者提供深入关注单一主题的机会； 4）推动肺部和重症监护医学的进一步研究