PROTEIN PHOSPHORYLATION IN YEAST VACUOLE FUSION

酵母液泡融合中的蛋白质磷酸化

• 批准号: 8171286
• 负责人: Alexey Jarrell Merz
• 金额: $ 0.24万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171286
• 关键词: Chimeric Proteins; Complex; Computer Retrieval of Information on Scientific Projects Database; Docking; Funding; Goals; Grant; Institution; Membrane Fusion; Phosphorylation; Proteins; Research; Research Personnel; Resources; Role; SNAP receptor; Source; United States National Institutes of Health; Vacuole; Yeasts; interest; rab GTP-Binding Proteins

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in the roles of several proteins involved in yeast vacuole membrane fusion, including a Rab GTPase (Ypt7p), its effector complex (HOPS), and vacuolar SNARE proteins (Vam3p, Vam7p, Vti1p, Nyv1p). Our goal is to generate a phosphorylation profile of known docking and fusion proteins, and to identify new fusion machinery.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们对涉及酵母液泡膜融合的几种蛋白质的作用感兴趣，包括RAB GTPase（YPT7P），其效应子络合物（HOPS）和液泡SNARE蛋白（VAM3P，VAM7P，VTI1P，NYV1P，NYV1P）。我们的目标是生成已知的对接和融合蛋白的磷酸化曲线，并确定新的融合机械。