IMAGE GUIDED THERAPY CENTER

影像引导治疗中心

• 批准号: 8170374
• 负责人: Ferenc A Jolesz
• 金额: $ 546.64万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170374
• 关键词: Ablation; Address; Area; Biomedical Engineering; Clinical; Clinical Investigator; Collaborations; Commit; Communities; Computer Retrieval of Information on Scientific Projects Database; Development; Drug Delivery Systems; Focused Ultrasound Therapy; Funding; Future; Goals; Grant; Hospitals; Image; Institution; Interdisciplinary Study; Intervention; Metabolic; Methods; Mission; Operative Surgical Procedures; Prostate; Research; Research Infrastructure; Research Personnel; Resources; Robotics; Scientist; Services; Site; Source; Technology; Testing; Therapeutic; Training; Translational Research; United States National Institutes of Health; Woman; biomedical resource; clinical application; clinical infrastructure; clinically relevant; image guided therapy; innovation; innovative technologies; molecular imaging; multidisciplinary; neurosurgery; new technology; novel; programs; public health relevance; technology development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): We are requesting continuation of funds for the National Biomedical Resource Center in Image-guided Therapy (NCIGT) at the Brigham & Women's Hospital. The Center provides a unique, centralized infrastructure for translational research in the area of image-guided therapy. The multidisciplinary program involves clinical investigators, biomedical engineers, and basic scientists in promoting and advancing IGT methods and related innovative clinical applications. We will develop and make available new, clinically relevant technologies in six discrete TRD Core Projects: 1) Computational Core; 2) Imaging Core; 3) Image- Guidance Core; 4) Neurosurgery Core; 5) Prostate Core and 6) Focused Ultrasound Therapy Core. These key research initiatives represent the technical and clinical infrastructure of the Resource. They are anticipated to have significant effect on several future IGT methods and clinical applications. We will combine forces with 7 independently funded Collaborations (DBPs) that address various essential technical or clinical aspects of IGT and our contribution will have significant clinical impact. Our goal is to combine current advances in the field of imaging (like Molecular Imaging, Functional and Metabolic Imaging) with advanced therapies (like MRI-guided Focused Ultrasound ablation or targeted drug delivery, endoscopic surgery or robotics) to achieve less invasive, safer and more effective therapeutic options. All IGT developments and applications will be tested and validated either on our site or at our collaborators, or distributed directly as a service to the growing IGT community. Our overarching goal is to continue being the leading National Center that reaching effectively across a broad range of constituencies through service, training and dissemination of the novel technologies and methods under development in this Resource. PUBLIC HEALTH RELEVANCE: The overarching impetus for this application is to advance and propagate novel image-guided therapy technologies, effectively producing strengthened multidisciplinary research efforts and an infrastructure commensurate with sophisticated technology development. We are also committed to making our technology broadly available to a large community of clinician. Our mission is to develop and implement novel, innovative technologies to decrease the invasiveness of surgeries and interventions.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 描述（由申请人提供）：我们请求继续为布莱根妇女医院的国家影像引导治疗生物医学资源中心 (NCIGT) 提供资金。该中心为图像引导治疗领域的转化研究提供了独特的、集中的基础设施。该多学科项目涉及临床研究人员、生物医学工程师和基础科学家，致力于促进和推进 IGT 方法及相关创新临床应用。我们将在六个独立的 TRD 核心项目中开发并提供新的临床相关技术：1）计算核心； 2）成像核心； 3）图像引导核心； 4）神经外科核心； 5) 前列腺核心和 6) 聚焦超声治疗核心。这些关键研究举措代表了该资源的技术和临床基础设施。预计它们将对未来的几种 IGT 方法和临床应用产生重大影响。我们将与 7 个独立资助的合作组织 (DBP) 合作，解决 IGT 的各种基本技术或临床问题，我们的贡献将产生重大的临床影响。我们的目标是将成像领域的最新进展（如分子成像、功能和代谢成像）与先进的疗法（如 MRI 引导的聚焦超声消融或靶向药物输送、内窥镜手术或机器人技术）相结合，以实现侵入性更小、更安全和更安全的治疗。更有效的治疗选择。所有 IGT 开发和应用程序都将在我们的网站或我们的合作者处进行测试和验证，或者作为服务直接分发给不断发展的 IGT 社区。我们的总体目标是继续成为领先的国家中心，通过服务、培训和传播本资源中正在开发的新技术和方法，有效地覆盖广泛的支持者。 公共健康相关性：该应用的首要推动力是推进和传播新颖的图像引导治疗技术，有效地加强多学科研究工作以及与复杂技术发展相称的基础设施。我们还致力于让广大临床医生广泛使用我们的技术。我们的使命是开发和实施新颖的创新技术，以减少手术和干预的侵入性。