CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 7562923
• 负责人: FRANK C ARNETT
• 金额: $ 39.24万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7562923
• 关键词: Acquired Immunodeficiency Syndrome; Award; Bioinformatics; Biological Markers; Biometry; Cancer Center; Class; Clinical; Clinical Cancer Center; Clinical Investigator; Clinical Research; Collaborations; Communities; Community Health; Computer Retrieval of Information on Scientific Projects Database; DNA Microarray Chip; DNA Microarray format; Dental Assistants; Discipline; Disease; Doctor of Medicine; Doctor of Philosophy; Ethics; Evidence Based Medicine; Faculty; Feasibility Studies; Funding; Genotype; Grant; Health; Health Sciences; Home environment; Hospitals; Human; Image; Immunologic Monitoring; Industry; Information Sciences; Institutes; Institution; Laboratories; Magnetic Resonance Imaging; Master' s Degree; Medical center; Mentors; Methods; Molecular Medicine; National Center for Research Resources; Nursing Schools; Participant; Postdoctoral Fellow; Productivity; Proteomics; Public Health Schools; Research; Research Design; Research Infrastructure; Research Personnel; Resources; Reverse Transcriptase Polymerase Chain Reaction; SECTM1 gene; Satellite Hospitals; School Nursing; Schools; Science; Scientist; Services; Source; Students; Teaching Hospitals; Technology; Texas; Thinking; Time; Translational Research; United States National Institutes of Health; Universities; biomedical informatics; innovation; medical schools; medical specialties; novel; pre-doctoral; school health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Regarding AIDS The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include those from the UTHSC-H component degree granting schools, including its School of Medicine, School of Public Health, Graduate School of Biomedical Sciences, School of Health Information Sciences, School of Nursing, Dental School and Institute of Molecular Medicine (IMM), as well as collaborating faculty/facilities from the UT M.D. Anderson Cancer Center (MDACC) and which also is located in the TMC. The academic "home" for the CCTS will be located in 11,422 sq ft of newly renovated and CCTS-designated space at the UTH Medical School which is physically joined to the Memorial Hermann Hospital (MHH) and serves as its partner and major teaching hospital. The CCTS "home" will administer all aspects of the CCTS and provide space and resources for faculty and trainees, along with expertise in study design, biostatistics, regulatory issues, ethics, and bioinformatics, and funding of Pilot and Feasibility Studies, provision of resources and protected time for clinical and translational faculty and trainees and interactions/collaborations with the various communites and industry. For Participant and Clinical Interactions Resources (PCIR), the CCTS will subsume the UTHSC-H General Clinical Research Center (GCRC) at MHH, the satellite UTHSC-H GCRC at Brownsville, Texas, and, in part, the MDACC Clinical and Translational Research Center to enhance research productivity and efficiency. In its Educational Component, the CCTS will subsume, in part, the current Center for Clinical Research and Evidence-Based Medicine, which has developed and currently provides formal classes, mentoring, and a Masters Degree in Clinical Research (MCR) at UTHSC-H, and an active NCRR K30 award at MDACC. Also proposed in the application is a novel T32 application offering combinations of Masters and PhD degrees in Community Health Sciences,'Biomedical Sciences and/or Biomedical Informatics, primarily for pre-doctoral students, and a K12 application for post-doctoral trainees and junior faculty. The CCTS also will subsume Core Translational Laboratories, including a Genotyping/Sequencing Corel a Biomarkers Core offering DNA Microarray, RT-PCR and Proteomics services , an Immune Monitoring Core, an MRI Imaging Core, and a Biobanking Core. A CCTS "Think Tank" comprised of highly accomplished translational and clinical Investigators, basic scientists and educators, and community representatives, will come together as an "engine for innovation" to bring forward and recommend the application of novel and emerging scientific information, methods and technologies to research into human health and diseases across specialties, disciplines and communities.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 关于艾滋病 德克萨斯大学休斯顿健康科学中心 (UTHSC-H) 提议在德克萨斯州休斯顿的德克萨斯医学中心 (TMC) 建立临床和转化科学中心 (CCTS)。 参与 CCTS 的教师和学员将包括 UTHSC-H 组成学位授予学校的教师和学员，包括其医学院、公共卫生学院、生物医学研究生院 科学学院、健康信息科学学院、护理学院、牙科学院和分子医学研究所 (IMM)，以及同样位于 TMC 的 UT M.D. 安德森癌症中心 (MDACC) 的合作教师/设施。 CCTS 的学术“家”将位于 UTH 医学院新装修的 11,422 平方英尺的 CCTS 指定空间内，该空间位于 物理上加入了赫尔曼纪念医院 (MHH)，并作为其合作伙伴和主要教学医院。 CCTS“家”将管理 CCTS 的各个方面，并为教师和学员提供空间和资源，以及研究设计、生物统计学、监管问题、伦理学和生物信息学方面的专业知识，以及试点和可行性研究的资助、资源的提供和受保护的时间 临床和翻译教师和实习生以及与各个社区和行业的互动/合作。对于参与者和临床互动资源 (PCIR)，CCTS 将纳入位于 MHH 的 UTHSC-H 一般临床研究中心 (GCRC)、位于布朗斯维尔的卫星 UTHSC-H GCRC、 德克萨斯州，以及 MDACC 临床和转化研究中心，以提高研究生产力和效率。在其教育部分中，CCTS 将部分纳入当前的临床研究和循证医学中心，该中心已在 UTHSC-H 开发并目前提供正式课程、指导和临床研究硕士学位 (MCR) ，以及 MDACC 的活跃 NCRR K30 奖。该申请中还提出了一种新颖的 T32 申请，主要针对博士前学生，提供社区健康科学、生物医学科学和/或生物医学信息学硕士和博士学位的组合，以及针对博士后学员和初级教师的 K12 申请。 CCTS 还将纳入核心转化实验室，包括 基因分型/测序 Corel 是一个提供 DNA 微阵列、RT-PCR 和蛋白质组学服务的生物标志物核心、一个免疫监测核心、一个 MRI 成像核心和一个生物样本库核心。 CCTS“智囊团”由卓有成就的转化和临床研究人员、基础科学家和教育工作者组成， 社区代表将齐聚一堂，作为“创新引擎”，提出并推荐新颖和新兴的科学信息、方法和技术的应用，以跨专业、学科和社区研究人类健康和疾病。