SC COBRE: PROTEIN SCIENCE CORE

SC COBRE：蛋白质科学核心

• 批准号: 8168045
• 负责人: Christopher Davies
• 金额: $ 12.91万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168045
• 关键词: Behavior; Calorimetry; Centers of Research Excellence; Circular Dichroism; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Production; Proteins; Pseudomonas; Quinolones; Research; Research Personnel; Resources; Science; Signal Transduction; Source; United States National Institutes of Health; light scattering

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Protein Science Core has continued to support the activities of the COBRE investigators. Specifically, it has been used to over-produce and purify several proteins, and to characterize their biophysical behavior using circular dichroism, dynamic light scattering and isothermal calorimetry. Most notably, Dr. Yong-mei Zhang, who is a new COBRE Investigator, has begun to use the lab extensively for the production of several proteins involved in Pseudomonas quinolone signaling.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 蛋白质科学核心继续支持毛cor研究者的活动。 具体而言，它已用于过度生产和净化几种蛋白质，并使用圆形二色性，动态光散射和等温量热法来表征其生物物理行为。最值得注意的是，是一名新的鞋底研究员的杨Zhang博士已开始广泛使用该实验室来生产涉及假单胞菌奎诺酮信号传导的几种蛋白质。