2008-2010 Lysosomes & Endocytosis Gordon Research Conference

2008-2010 溶酶体

• 批准号: 7480581
• 负责人: Frances M. Brodsky
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7480581
• 关键词: Academy; Area; Biology; Cytokinesis; Defect; Development; Developmental Biology; Disease; Endocytosis; Funding; Growth; Health; Hereditary Disease; Human; Immunity; Infection; International; Lysosomes; Malignant Neoplasms; Membrane Protein Traffic; Myopathy; Neurologic; Participant; Pathway interactions; Play; Request for Proposals; Research; Resistance; Role; Series; Signal Transduction; Staging; Viral; abstracting; novel; pathogen; posters; programs; symposium

DESCRIPTION (provided by applicant): This proposal requests funding for partial support for two sequential meetings on Lysosomes and Endocytosis as part of the Gordon Research Conference series to be held in Proctor Academy, Andover, NH from June 22-27th 2008 and again at the end of June 2010. This conference has a tradition of forty years as a venue for presentation of cutting edge research in the area of membrane traffic in the endocytic pathway. In recent years it has become apparent that the endocytic pathway plays important roles in new areas such as development, cytokinesis, signalling, immunity to pathogens, growth control and genetic diseases. This gives the Chair and Vice Chair an excellent opportunity to plan ahead to include new directions in the programs. We are therefore applying for funding for the 2008 and 2010 meetings, in order to plan to include new areas coordinating the basic pathways with disease states including, muscle disease, developmental defects, neurological defects and cancer, as well as infection and immunity. The aim of this meeting is to gather a total of 40 speakers and 8 discussion leaders, representing critical areas in research in endocytosis and lysosome biology and explore novel related areas of research. The program for 2008 will have a keynote presentation and 8 sessions encompassing different stages of the endocytic pathway, the role of the lysosome in disease, pathogen resistance and developmental biology.15 speakers will be selected from abstracts submitted and one session will be devoted to discussion of new directions. In addition, two evening poster sessions will permit all participants to contribute to these topics. For the 2010 conference, the plan is to expand the focus on membrane traffic in muscle disease and the role of the endocytic pathway in cancer, as well as continue to include infection and immunity and lysosomal diseases. The significance of this application is that the Lysosomes and Endocytosis GRC is the key international meeting in this field. The topic has a clear impact on human health with the endocytic pathway playing a role in viral entry, pathogen resistance and lysosome-related diseases, as well as recent implications for development, myopathy and cancer.

描述（由申请人提供）：该提案要求为两次连续的关于溶酶体和内吞作用的会议提供部分支持，作为戈登研究会议系列的一部分，将于 2008 年 6 月 22 日至 27 日在新罕布什尔州安多弗普罗克特学院举行，并再次在2010 年 6 月底。该会议已有四十年的传统，作为展示内吞途径膜运输领域前沿研究的场所。近年来，内吞途径在发育、胞质分裂、信号传导、病原体免疫、生长控制和遗传疾病等新领域中发挥着重要作用已经变得越来越明显。这为主席和副主席提供了一个绝佳的机会来提前计划，将新的方向纳入计划中。因此，我们正在为2008年和2010年的会议申请资金，以便计划纳入协调疾病状态基本途径的新领域，包括肌肉疾病、发育缺陷、神经缺陷和癌症，以及感染和免疫。本次会议的目的是聚集 40 名发言人和 8 名讨论主持人，代表内吞作用和溶酶体生物学研究的关键领域，并探索新颖的相关研究领域。 2008年的计划将有一个主题演讲和8场会议，涵盖内吞途径的不同阶段、溶酶体在疾病中的作用、病原体抗性和发育生物学。将从提交的摘要中选出15名发言者，其中一场将专门讨论的新方向。此外，两次晚间海报会议将允许所有参与者为这些主题做出贡献。 2010 年会议的计划是扩大对肌肉疾病中的膜运输和内吞途径在癌症中的作用的关注，并继续包括感染和免疫以及溶酶体疾病。本次申请的意义在于溶酶体和内吞作用GRC是该领域的关键国际会议。该主题对人类健康具有明显的影响，内吞途径在病毒进入、病原体抵抗和溶酶体相关疾病中发挥作用，以及对发育、肌病和癌症的最新影响。