H-19197 PHACS PH 200 ADOLESCENT MASTER PROTOCOL (AMP)

H-19197 PHACS PH 200 青少年主方案 (AMP)

• 批准号: 8356682
• 负责人: William Thomas Shearer
• 金额: $ 8.18万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-12-01 至 2011-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8356682
• 关键词: Adolescent; Age Distribution; Behavioral; Cardiac; Cardiovascular Diseases; Child; Clinical Research; Cohort Studies; Enrollment; Exposure to; Funding; Grant; Growth; HIV; HIV Infections; Hearing; Human papilloma virus infection; Language; Metabolic; National Center for Research Resources; Neurologic; Perinatal; Perinatal Exposure; Principal Investigator; Protocols documentation; Research; Research Design; Research Infrastructure; Resources; Risk Factors; Sexual Maturation; Source; United States National Institutes of Health; antiretroviral therapy; bone health; cost; neurodevelopment; prospective

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. ABSTRACT This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy on pre-adolescents and adolescents with perinatal HIV infection. A group of HIV-uninfected children with perinatal exposure to HIV from a similar sociodemographic background and age distribution will be enrolled for comparison. Domains to be investigated include growth and sexual maturation, metabolic risk factors for cardiovascular disease, cardiac function, bone health, neurologic, neurodevelopment, language, hearing and behavioral function, and human papillomavirus (HPV) infection.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 抽象的 这是一项前瞻性队列研究，旨在定义HIV感染和抗逆转录病毒疗法对围产期HIV感染的预科和青少年的影响。将招募一群来自类似的社会人口统计学背景和年龄分布的HIV未感染的儿童，以进行比较。 要研究的领域包括生长和性成熟，心血管疾病的代谢危险因素，心脏功能，骨骼健康，神经系统，神经发育，语言，听力和行为功能以及人类乳头瘤病毒（HPV）感染。