DRP: Developmental Research Program

DRP：发展研究计划

基本信息

批准号：
8055512
负责人：
Chung Lee
金额：
$ 22.03万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-03-31 至 2014-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8055512
关键词：
Advisory Committees Award Behavior Bioinformatics Biological Assay Biological Markers Biometry Cancer Center Cell Adhesion Cells Cellular biology Chad Chemopreventive Agent Chicago Clinical Collaborations Conflict of Interest Data Development Elements Endoglin Epithelial Cells Evaluation Extramural Activities Faculty Freezing Funding Funding Agency Gelatinase A Gene Expression Genes Genistein Grant HSPB1 gene Individual Investigation Laboratories MAPK14 gene Malignant Neoplasms Malignant neoplasm of prostate Manuscripts Matrix Metalloproteinases Measures Mediating Medicine Methods Minority Molecular Profiling Monitor Nanotechnology Neoplasm Metastasis Normal Cell Patients Peer Review Phase I Clinical Trials Phase II Clinical Trials Phosphorylation Pilot Projects Positioning Attribute Prevention Procedures Process Productivity Progress Reports Prostate Publishing RNA RNA amplification Radical Prostatectomy Recording of previous events Recruitment Activity Regulation Relative (related person)Reproduction spores Research Research Personnel Review Committee Sampling Secure Specimen Techniques Time Tissues United States National Institutes of Health Universities Woman base cancer cell cell motility design flexibility innovation interest laser capture microdissection meetings member men mitogen-activated protein kinase p38 nanostructured neoplastic cell phase 2 study professor programs randomized trial tumor

项目摘要

The Prostate SPORE Developmental Research Program operates under the direction of the Administrative Core. The SPORE sets aside $150,000 each year (plus Institutional support) to fund 4-5 feasibility projects to generate data that will enable the investigator to apply for extramural funds. In January of each year a request for pilot projects is sent out to all members of the Cancer Centers at Northwestern University and the University of Chicago. There is an established process for peer review of pilot projects by an ad hoc review committee. The SPORE Executive Committee takes priority scores and makes the final funding decision. The process is flexible, in that pilot projects can be elevated to replace full SPORE projects and pilot projects can be terminated if progress is not satisfactory. For example, Project 4 (PI: Bergan and Catalona) and Project 3 (PI: Weichselbaum and Stadler) were both pilot projects that were elevated to full project status based on significant progress made. And Project 2 (PI: Crawford, Gapstur and Lee) has also been elevated from a pilot project. Additionally, an investigator may submit a pilot project at any time to the SPORE Director. It is reviewed by the ad hoc committee and if favorably reviewed and if adequate funds exist, it may receive funding. Therefore, the Developmental Research Program enables the Prostate SPORE to expand investigator participation to bring more investigators into the field to maximize our research efforts on prostate cancer. A detailed description of pilot projects is described in Section XII of the application

前列腺孢子发育研究计划在行政核心的指导下运行。孢子每年预留15万美元（加机构支持），以资助4-5个可行性项目，以生成数据，使研究人员能够申请校外资金。每年一月，向西北大学和芝加哥大学的癌症中心的所有成员发送了一项试点项目的要求。临时审查委员会有一个既定的过程，可以对试点项目进行同行审查。孢子执行委员会获得优先分数，并做出最终的资金决定。该过程是灵活的，因为可以提升试点项目以替换完整的孢子项目，如果进展不满意，则可以终止试点项目。例如，项目4（PI：Bergan和Catalona）和项目3（PI： Weichselbaum和Stadler）都是试点项目，这些项目都根据取得了重大进展。和项目2（PI：Crawford，Gapstur和Lee）也从试点项目中提升。此外，调查员可以随时向孢子主管提交试点项目。它由临时委员会进行审查，如果经过好评，如果存在足够的资金，则可能会获得资金。因此，发展研究计划使前列腺孢子能够扩大研究人员的参与，以将更多的研究人员带入该领域，以最大程度地提高我们对前列腺癌的研究工作。该应用程序的第十二节介绍了试点项目的详细说明