2008 Cell Biology of the Neuron

2008 神经元细胞生物学

基本信息

批准号：
8113962
负责人：
JOSHUA M KAPLAN
金额：
$ 4.37万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-01 至 2012-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8113962
关键词：
Aging Alzheimer&apos s Disease Anxiety Autistic Disorder Axon Behavior Disorders Behavioral Biological Biological Models Brain Caenorhabditis elegans Cells Cellular Neurobiology Cellular biology Child Development Child health care Cognition Disorders Communication Complex Defect Dendrites Development Disease Drug Addiction Drug Tolerance Ensure Funding Human Image Inherited Institutes International Mental Health Mission Molecular Molecular Genetics Mood Disorders Morphogenesis National Institute of Child Health and Human Development National Institute of Drug Abuse National Institute of General Medical Sciences National Institute of Mental Health National Institute of Neurological Disorders and Stroke National Institute on Alcohol Abuse and Alcoholism Neuronal Plasticity Neurons Neurophysiology - biologic function Parkinson Disease Participant Request for Proposals Research Research Personnel Scientist Signal Transduction Supporting Cell Synapses Synaptic plasticity Time Woman Work base career interdisciplinary approach interest meetings neurodevelopment neuromechanism posters symposium

项目摘要

DESCRIPTION (provided by applicant): The "Cell Biology of the Neuron" Gordon Conference, to be held for the eighth time in June 2008, has become the premier international meeting for discussing progress in the rapidly moving field of cellular neurobiology. The focus of the meeting will be on the cell biological aspects of neural function. The meeting will encompass a diverse set of interdisciplinary approaches, including genetic, molecular, cellular, biophysical, and behavioral approaches to understanding the brain. A diverse set of model systems will be represented at the meeting, ranging from C. elegans to humans. This year the following themes will be covered: synapse development, pre-synaptic mechanisms, post-synaptic signaling, axon and dendrite morphogenesis, cortical connectivity, imaging circuits, and synaptic plasticity. The chosen speakers are among the most active in the field and are also articulate thinkers who should generate useful discussion by integrating their work and ideas with those in other fields. The format consists of 20 minute talks followed by a discussion of 10 minutes or more. The meeting roster contains a mixture of promising young scientists near the beginning of their careers and established scientists. Nine of the speakers are women and five are from outside the US. In addition, eight slots are being kept open to select speakers for short talks on exciting, late-breaking developments. Most participants (except speakers) will present posters on their work, ensuring maximum communication and exchange of ideas among participants. With its interdisciplinary focus on neural mechanisms, this conference is of special interest for understanding affective and behavioral disorders, hereditary defects in brain development, mental health and drug addiction. The emphasis on neural development and plasticity has relevance for child health and development. The speakers include investigators who are specifically studying the molecular basis of drug tolerance and addiction, affective and cognitive disorders (e.g. anxiety and autism), hereditary defects in brain development, and diseases of aging such as Alzheimer's and Parkinson,s diseases. The conference should be of great potential interest to the missions of institutes including NIMH, NINDS, NICHD, NIA, NIDA and NIAAA. This proposal requests fund to support the "Cell Biology of the Neuron" Gordon Research Conference, to be held in June 2008. This conference brings together a diverse set of neurobiologists, all of whom study the fundamental building blocks of the brain, neurons and synapses. In particular, this meeting will highlight recent discoveries in how the brain develops its complex set of synaptic connections, and how these connections are modified during development, or in different disease states. Thus, this meeting will further the mission of several institutes, including NIGMS, NINDS, NIMH, NIDA, NEI, and NIAAA. .

描述（由申请人提供）：“神经元细胞生物学”戈登会议将于 2008 年 6 月举行第八次，已成为讨论快速发展的细胞神经生物学领域进展的首要国际会议。会议的重点将是神经功能的细胞生物学方面。会议将涵盖多种跨学科方法，包括遗传、分子、细胞、生物物理和行为方法来理解大脑。会议将展示一系列不同的模型系统，从秀丽隐杆线虫到人类。今年将涵盖以下主题：突触发育、突触前机制、突触后信号传导、轴突和树突形态发生、皮质连接、成像电路和突触可塑性。选定的演讲者是该领域最活跃的人，也是善于表达的思想家，他们应该通过将自己的工作和想法与其他领域的工作和想法相结合来引发有用的讨论。其形式包括 20 分钟的演讲和 10 分钟或更长时间的讨论。会议名单中既有即将开始职业生涯的有前途的年轻科学家，也有已成名的科学家。其中九位演讲者是女性，五位来自美国以外的地区。此外，还保留了八个席位，供选定的演讲者就令人兴奋的最新进展进行简短的演讲。大多数参与者（演讲者除外）将展示他们的工作海报，以确保参与者之间最大程度的沟通和思想交流。由于其跨学科重点关注神经机制，这次会议对理解情感和行为障碍、大脑发育的遗传性缺陷、心理健康和毒瘾特别感兴趣。对神经发育和可塑性的重视与儿童的健康和发展相关。演讲者包括专门研究药物耐受性和成瘾、情感和认知障碍（例如焦虑和自闭症）、大脑发育遗传性缺陷以及阿尔茨海默病和帕金森病等衰老疾病的分子基础的研究人员。此次会议应该对 NIMH、NINDS、NICHD、NIA、NIDA 和 NIAAA 等机构的使命具有巨大的潜在兴趣。该提案请求资金支持将于 2008 年 6 月举行的“神经元细胞生物学”戈登研究会议。该会议汇集了不同类型的神经生物学家，他们都研究大脑、神经元和突触的基本组成部分。特别是，这次会议将重点介绍大脑如何发展其复杂的突触连接集，以及这些连接在发育过程中或在不同疾病状态下如何被修改的最新发现。因此，本次会议将进一步推进包括 NIGMS、NINDS、NIMH、NIDA、NEI 和 NIAAA 在内的多个机构的使命。。