CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8365148
• 负责人: JOSEPH G VERBALIS
• 金额: $ 71.84万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365148
• 关键词: Acquired Immunodeficiency Syndrome; Clinical Sciences; Research; Research Infrastructure; Translational Research; Universities

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated hospital systems and research institutes: MedStar Health and Research Institute (MSH/MRI), Oak Ridge National Laboratory (ORNL), and the Washington, DC Veteran's Affairs Medical Center (WVAMC). This application is a resubmission of a revised previous application from 2008. The specific aims of GHUCCTS are: 1) To speed improvements in human health by stimulating innovative, multidisciplinary, and cross-institutional research among the GHUCCTS investigators; 2) To support the careers of clinical and translational investigators through a wide variety of didactic educational programs coupled with focused mentorship; and 3) To enhance clinical and translational research on underserved populations, both in the Washington DC region and nationally, prominently including minorities, the aged, and the disabled. To accomplish these aims, we will integrate our existing NCRR-funded programs, including two existing MOI-funded GCRCs at GU and HU and our successful multi-institutional K30 program, with a new and innovative hospital, practice- based, laboratory-based, and community-based research infrastructure for clinical and translational science. The new capabilities that we will build as part of GHUCCTS include a coordinated multi-institutional biomedical informatics infrastructure, an expanded clinical research operation that will create new community-based clinical research units, a new community engagement resource component to support and enhance community-based research, expanded resources in regulatory knowledge and support that will be intimately integrated with ethics, and new funded research projects in the development of novel translational methodologies in collaboration with the supercomputing and systems genetics translational capabilities of ORNL. The integration of these clinical and translational resources across the GHUCCTS institutions will be accompanied by a strong research education, training, and career development program that will train a new generation of researchers, including a new Clinical and Translational Scholars K12 program and a new Masters degree program in clinical and translational science. Our innovative approach to collaboration and multi-disciplinary research involving multiple major research-intensive institutions of our region, in collaboration with the national CTSA network, will help our institutions and our community in the Washington, DC area benefit from the generation and application of new discoveries in clinical and translational science.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 Georgetown-Howard大学临床和转化科学中心（GHUCCTS）是乔治敦大学（GU）和霍华德大学（HU）的主要合作伙伴关系，与3个附属医院系统和研究机构：MedStar Health and Research Institute（MSH/MRI），Oak Ridge National Laboration（Ornl），以及华盛顿州的事务中心，Oak Ridge国家实验室（Oak Ridge National Laboratory（Oak Ridge National））该应用程序是对2008年修订的先前应用程序的重新提交。GHUCCT的具体目的是：1）通过刺激GHUCCTS研究人员之间的创新，多学科和跨机构研究来加快人类健康的改善； 2）通过各种教学教育计划以及专注的指导来支持临床和翻译调查员的职业； 3）在华盛顿特区地区以及全国范围内，包括少数族裔，老年人和残疾人，以增强服务不足人群的临床和转化研究。为了实现这些目标，我们将将现有的NCRR资助的计划整合在一起，包括GU和HU的两个现有MOI资助的GCRC以及我们成功的多机构K30计划，以及一个新的，创新的医院，基于实践的，基于实验室的，基于实验室的和基于社区的临床和转换科学的基于社区的研究基础设施。我们将作为GHUCCT的一部分建立的新功能包括协调的多机构生物医学信息学基础架构，这是一个扩大的临床研究操作，该操作将创建新的基于社区的临床研究单位，这是一种新的社区参与资源，以支持和增强社区资源的基于社区的研究，并将其融合在宗教知识方面扩展的研究以及新的基于社区的研究的发展，并将其与新的研究相结合，并将其与新的研究融合在一起。超级计算和系统遗传学的转化能力。这些临床和转化资源在整个GHUCCT机构中的整合将伴随着强大的研究教育，培训和职业发展计划，该计划将培训新一代的研究人员，包括新的临床和翻译学者K12计划和新的临床和翻译科学硕士学位课程。我们与国家CTSA网络合作的多个主要研究密集型机构的合作和多学科研究的创新方法将帮助我们的机构和我们的机构和我们的社区在华盛顿特区地区受益于临床和翻译科学领域的新发现和应用。