CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8173904
• 负责人: JOSEPH G VERBALIS
• 金额: $ 88.71万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173904
• 关键词: Research; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated hospital systems and research institutes: MedStar Health and Research Institute (MSH/MRI), Oak Ridge National Laboratory (ORNL), and the Washington, DC Veteran's Affairs Medical Center (WVAMC). This application is a resubmission of a revised previous application from 2008. The specific aims of GHUCCTS are: 1) To speed improvements in human health by stimulating innovative, multidisciplinary, and cross-institutional research among the GHUCCTS investigators; 2) To support the careers of clinical and translational investigators through a wide variety of didactic educational programs coupled with focused mentorship; and 3) To enhance clinical and translational research on underserved populations, both in the Washington DC region and nationally, prominently including minorities, the aged, and the disabled. To accomplish these aims, we will integrate our existing NCRR-funded programs, including two existing MOI-funded GCRCs at GU and HU and our successful multi-institutional K30 program, with a new and innovative hospital, practice- based, laboratory-based, and community-based research infrastructure for clinical and translational science. The new capabilities that we will build as part of GHUCCTS include a coordinated multi-institutional biomedical informatics infrastructure, an expanded clinical research operation that will create new community-based clinical research units, a new community engagement resource component to support and enhance community-based research, expanded resources in regulatory knowledge and support that will be intimately integrated with ethics, and new funded research projects in the development of novel translational methodologies in collaboration with the supercomputing and systems genetics translational capabilities of ORNL. The integration of these clinical and translational resources across the GHUCCTS institutions will be accompanied by a strong research education, training, and career development program that will train a new generation of researchers, including a new Clinical and Translational Scholars K12 program and a new Masters degree program in clinical and translational science. Our innovative approach to collaboration and multi-disciplinary research involving multiple major research-intensive institutions of our region, in collaboration with the national CTSA network, will help our institutions and our community in the Washington, DC area benefit from the generation and application of new discoveries in clinical and translational science.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目工作人员提供的补助金。 乔治城-霍华德大学临床和转化科学中心 (GHUCCTS) 是乔治城大学 (GU) 和霍华德大学 (HU) 的主要合作伙伴，拥有 3 个附属医院系统和研究机构： MedStar 健康与研究所 (MSH/MRI) 、橡树岭国家实验室 (ORNL) 和华盛顿特区退伍军人事务医疗中心 (WVAMC)。本申请是对 2008 年修订后的先前申请的重新提交。GHUCCTS 的具体目标是： 1) 通过刺激 GHUCCTS 研究者的创新、多学科和跨机构研究来加速人类健康的改善； 2) 通过各种教学教育计划和重点指导来支持临床和转化研究人员的职业生涯； 3) 加强对华盛顿特区和全国服务不足人群的临床和转化研究，主要包括少数族裔、老年人和残疾人。为了实现这些目标，我们将整合我们现有的 NCRR 资助项目，包括 GU 和 HU 的两个现有 MOI 资助的 GCRC 以及我们成功的多机构 K30 项目，与一家新的创新医院、基于实践、基于实验室、以及基于社区的临床和转化科学研究基础设施。作为 GHUCCTS 的一部分，我们将建立的新能力包括协调的多机构生物医学信息学基础设施、扩大的临床研究业务（将创建新的基于社区的临床研究单位）、新的社区参与资源组件以支持和增强基于社区的临床研究业务。研究、扩大与伦理学密切结合的监管知识和支持资源，以及与橡树岭国家实验室的超级计算和系统遗传学翻译能力合作开发新型转化方法的新资助研究项目。 GHUCCTS 机构中这些临床和转化资源的整合将伴随着强大的研究教育、培训和职业发展计划，该计划将培训新一代研究人员，包括新的临床和转化学者 K12 计划和新的硕士学位临床和转化科学项目。我们的创新合作和多学科研究方法涉及我们地区的多个主要研究密集型机构，并与国家 CTSA 网络合作，将帮助我们华盛顿特区的机构和社区从新的技术的产生和应用中受益。临床和转化科学的发现。