"Recruitment of a Bone and Cancer Early Stage Investigator"

“招募骨与癌症早期研究员”

基本信息

批准号：
7941054
负责人：
D Rick Sumner
金额：
$ 39.2万
依托单位：
RUSH UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-29 至 2012-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7941054
关键词：
Recruitment Bone Cancer Early Stage

项目摘要

DESCRIPTION (Provided by the applicant): The goal of this project is to continue the development of a Core Center in Bone and Cancer at Rush University Medical Center by facilitating the recruitment of a new early stage investigator to a tenure-track faculty position. The Medical Center has a large group of basic and translational researchers focusing on connective tissues, particularly bone, articular cartilage and tendons and ligaments. Two important strategic focus areas for the Medical Center include orthopedics and cancer, as evidenced by a number of building projects, new recruits and the nearly completed recruitment of a cancer director. As a cooperative venture between the Department of Anatomy & Cell Biology and the Department of Orthopedic Surgery, we have recently recruited a senior, NIH funded, faculty member with expertise in cancer biology into our newly established bone and cancer program. Through this grant mechanism, we now propose to expand the bone and cancer program by recruiting a laboratory-based early stage investigator who is committed to a career working with clinicians in the design and implementation of translational cancer research. We have already completed the initial search phase and have interviewed three outstanding candidates. Among these candidates, we have prioritized our ranking based on the "fit" between the candidate's research area and expressed desire to have a strong translational component and our clinical and basic science research strengths. The major mission of the Bone and Cancer is to advance patient treatment through improved understanding of cancer survival and metastasis mechanisms. A great deal is now being learned about the potential importance of cancer stem cells in resistance to treatment and the bone microenvironment in bone metastases. The development of a Bone and Cancer Core Center represents an ideal way to bolster cancer research activity at Rush since the great strengths in skeletal research and clinical orthopedic oncology can be leveraged to provide administrative and scientific support for the proposed activities.

描述（由申请人提供）：该项目的目的是通过促进新的早期调查员招募担任终身教师职位，以继续在Rush University Medical Center开发骨骼和癌症的核心中心。该医疗中心有大量的基本和翻译研究人员，专注于结缔组织，尤其是骨骼，关节软骨，肌腱和韧带。医疗中心的两个重要战略重点领域包括骨科和癌症，这是许多建筑项目，新的新兵以及几乎完成的癌症主管的招聘。作为部门之间的合作企业解剖与细胞生物学以及骨科手术系，我们最近招募了一名由NIH资助的高级，资助的教职员工，具有癌症生物学专业知识，进入了我们新建立的骨与癌症计划。通过这种赠款机制，我们现在建议通过招募一名基于实验室的早期研究者来扩大骨骼和癌症计划，该研究人员致力于与临床医生一起工作和实施转化癌症研究的职业。我们已经完成了初始搜索阶段，并采访了三名出色的候选人。在这些候选人中，我们根据候选人的研究领域的“拟合度”对排名进行了优先排名，并表示希望拥有强大的翻译成分以及我们的临床和基础科学研究的优势。骨骼和癌症的主要任务是通过改善对癌症存活和转移机制的了解来提高患者治疗。现在已经了解了很多关于癌症干细胞在耐药性和骨转移中骨微环境中潜在的重要性的了解。骨骼和癌症核心中心的发展代表了在Rush上加强癌症研究活动的理想方式，因为可以利用骨骼研究和临床骨科肿瘤学的巨大优势，以为所提出的活动提供行政和科学支持。