ERPLAB: Extensible, open source software for analysis of event-related potentials

ERPLAB：用于分析事件相关电位的可扩展开源软件

• 批准号: 7994242
• 负责人: STEVEN J LUCK
• 金额: $ 15.17万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2014-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7994242
• 关键词: Address; Adoption; Affective; Automation; Basic Science; Brain; Clinical Trials; Cognition; Cognitive; Communities; Complement; Computer software; Data; Data Analyses; Development; Diagnosis; Disease; Documentation; Effectiveness; Electrodes; Electroencephalography; Emotions; Environment; Event-Related Potentials; Explosion; Functional Magnetic Resonance Imaging; Goals; Human; Human Resources; Individual; Laboratories; Licensing; Linux; Measures; Methods; Mind; Motor; Neurology; Neurosciences; Patients; Perception; Performance; Pharmacologic Substance; Procedures; Process; Psychiatry; Psychology; Research; Research Personnel; Resolution; Running; Science; Scientific Advances and Accomplishments; Sensory; Source; Staging; Subgroup; System; Systems Analysis; Techniques; Testing; Translational Research; Writing; base; computer program; cost; cost effective; design; electric impedance; graphical user interface; improved; innovation; migration; millisecond; novel strategies; open source; programs; public health relevance; skills; software development; tool; ultra high resolution; user-friendly

DESCRIPTION (provided by applicant): This project continues the development and support of ERPLAB Toolbox, a Matlab-based open source software package for the analysis of event-related potential (ERP) data. ERPs provide information about brain activity related to perception, cognition, emotion, and action with millisecond resolution and are widely used to study a broad range of basic and translational science issues in psychology, neuroscience, psychiatry, neurology, and related fields. There has been an explosion in ERP research, but progress has been hampered by the limited abilities of commercial ERP analysis software and the lack of full-featured open source ERP analysis packages. This situation has slowed the development of new directions in ERP research, instead encouraging researchers to continue with existing approaches supported by the built-in functions of the available ERP analysis packages. ERPLAB Toolbox directly addresses these problems. It merges the functionality of an existing closed source ERP analysis system, ERPSS, with an open source EEG processing package, EEGLAB. EEGLAB provides the EEG processing functions that are the first steps in ERP analysis and a convenient graphical user interface (GUI). ERPLAB builds on EEGLAB by adding powerful tools for the subsequent stages of ERP analysis. All ERPLAB tools can be accessed from the GUI, and they can also be accessed from Matlab scripts to provide automation and customization. ERPLAB will provide powerful but easy-to-use tools for the basic analysis procedures that are commonly used by ERP researchers. It will also provide a set of advanced functions that are either currently in widespread use or are underutilized. This set of basic and advanced functions will greatly improve the quality and decrease the cost of ERP research. In addition, ERPLAB is designed to be easily extended by anyone with rudimentary programming skills. The community of users will therefore contribute to the development of ERPLAB, providing implementations of existing techniques that are very important to various subgroups of ERP researchers and allowing the development and dissemination of new tools that can advance the state of the art. A beta version of ERPLAB is now available, and the goal of the proposed project is to continue the development of the software and to provide the documentation and end-user support that is necessary to maximize the usefulness of the package. Over 500 researchers have already joined our effort, and we anticipate at least 2,000 users by the end of the proposed project period. By providing powerful processing tools to this large set of users, we hope to improve the analysis of data from current experimental paradigms and to help researchers to push the boundaries of science by making it easy for them to develop analysis tools that are not anticipated by current ERP analysis systems. PUBLIC HEALTH RELEVANCE: This software developed in this project will allow researchers to more accurately quantify and interpret brainwave data recorded from healthy individuals in basic science studies and from patients in translational science studies. It will allow research on normal and abnormal brain function to progress more rapidly, leading to a better understanding, diagnosis, and treatment of diseases of mind and brain.

描述（由申请人提供）：该项目继续开发和支持ERPLAB工具箱，ERPLAB工具箱是一种基于MATLAB的开源软件包，用于分析事件相关电位（ERP）数据。 ERP提供有关与毫秒分辨率有关的知觉，认知，情感和行动有关的大脑活动的信息，并广泛用于研究心理学，神经科学，精神病学，神经病学和相关领域的广泛基本和转化科学问题。 ERP研究发生了爆炸，但是商业ERP分析软件的能力有限和缺乏功能齐全的开源ERP分析软件包的能力受到阻碍。这种情况减慢了ERP研究中新方向的发展，而是鼓励研究人员继续采用可用ERP分析软件包内置功能支持的现有方法。 ERPLAB工具箱直接解决了这些问题。它将现有封闭源ERP分析系统ERPS的功能与开源EEG处理软件包EEGLAB合并。 EEGLAB提供的EEG处理功能是ERP分析和方便的图形用户界面（GUI）的第一步。 ERPLAB通过在EEGLAB上添加强大的工具为ERP分析的后续阶段构建。所有ERPLAB工具都可以从GUI访问，也可以从MATLAB脚本访问它们以提供自动化和自定义。 ERPLAB将为ERP研究人员常用的基本分析程序提供强大但易于使用的工具。它还将提供一组高级功能，这些功能当前正在广泛使用或未被充分利用。这组基本和高级功能将大大提高质量并降低ERP研究的成本。此外，ERPLAB的设计易于由具有基本编程技能的任何人进行扩展。因此，用户社区将有助于ERPLAB的开发，从而实施现有技术，这些技术对ERP研究人员的各个子组非常重要，并允许开发和传播可以推进最新状态的新工具。 现在可以使用Beta版的ERPLAB版本，而该项目的目标是继续开发软件，并提供文档和最终用户支持，以最大程度地提高软件包的实用性。超过500名研究人员已经加入了我们的努力，我们预计到拟议项目期结束时，至少有2,000名用户。通过为这组大量用户提供强大的处理工具，我们希望改善当前实验范式的数据分析，并通过使他们可以轻松地开发当前ERP分析系统预期的分析工具来帮助研究人员突破科学的界限。 公共卫生相关性： 该项目中开发的该软件将使研究人员能够更准确地量化和解释来自基础科学研究中健康个体和转化科学研究患者的脑电波数据。它将允许对正常和异常大脑功能的研究更快地进展，从而更好地理解，诊断和治疗思维和大脑疾病。