MICHIGAN ALZHEIMER?S DISEASE RESEARCH CENTER D(LONGITUDINAL COHORT) D MINORITY S

密歇根阿尔茨海默病研究中心 D（纵向队列）D 少数民族 S

• 批准号: 7376577
• 负责人: NORMAN LOUIS FOSTER
• 金额: $ 0.15万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-05 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7376577
• 关键词: Alzheimer' s disease; complement; dementia; emotions; family; health; information systems; learning; literature survey; medical records; memory; rest; thinking; university

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is being performed to learn more about the types of symptoms that develop in patients with Alzheimer's disease and related disorders. This study is a complement to an identical study being conducted at the University of Michigan Neurology Clinic. This study is conducted at the Ypsilanti Satellite with a goal of reaching target populations of underrepresented minorities. Participants in the study do not have to change their regular medical care. By observing how symptoms change over time, we hope to learn more about when and why particular symptoms develop. Individuals invited to enroll in this study are in good general health and have uncomplicated Alzheimer's disease or another related disorder that can affect memory or thinking ability. Once a participant enrolls in the study, he or she will be examined every six months at the Ypsilanti Satellite. Participants will also be given memory testing once a year. If a participant is no longer able to return for visits, study staff will contact the participant or participant's family by telephone to ask questions about the participant's health and progression of illness. These contacts will continue throughout the rest of the participant's life or until the participant withdraws from the study. Whenever possible, study procedures will occur at the same time as examinations required for regular medical care. However, if no regular clinical care is needed, participants will be asked to complete a 'study only' visit. As part of the study, medical records from regular Alzheimer's care will also be reviewed. Information from regular clinical care and study visits will be stored in a database at the University of Michigan. This data will be used in three ways: First, investigators named on the informed consent may access relevant data for participants they see prior to visits in order to monitor a participant's progression and prepare for their clinical evaluation. Second, separate research projects that are approved by the IRB and the Executive Committee may use data for research on dementia. In accordance with HIPAA, only the minimum necessary data would ever be provided to an approved separate project. Third, the data will also be stored in a national database at the National Alzheimer's Coordinating Center, a National Institutes of Health-funded Center. The data that goes to the NACC does not contain names, medical record numbers, or social security

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。进行这项研究是为了更多地了解阿尔茨海默病和相关疾病患者出现的症状类型。这项研究是对密歇根大学神经病学诊所正在进行的一项相同研究的补充。这项研究是在伊普西兰蒂卫星上进行的，目的是覆盖代表性不足的少数族裔的目标人群。研究参与者不必改变他们的常规医疗护理。通过观察症状如何随时间变化，我们希望更多地了解特定症状出现的时间和原因。受邀参加这项研究的个人总体健康状况良好，患有无并发症的阿尔茨海默病或其他可能影响记忆或思维能力的相关疾病。一旦参与者报名参加研究，他或她将每六个月在伊普西兰蒂卫星中心接受一次检查。参与者还将每年接受一次记忆测试。如果参与者无法再返回探访，研究人员将通过电话联系参与者或参与者的家人，询问有关参与者的健康状况和疾病进展的问题。这些联系将持续到参与者的余生或直到参与者退出研究。只要有可能，研究程序将与常规医疗护理所需的检查同时进行。然而，如果不需要定期临床护理，参与者将被要求完成“仅研究”访问。作为研究的一部分，还将审查定期阿尔茨海默病护理的医疗记录。定期临床护理和研究访问的信息将存储在密歇根大学的数据库中。这些数据将以三种方式使用：首先，知情同意书上指定的研究人员可以访问他们在访问之前见过的参与者的相关数据，以监测参与者的进展并为他们的临床评估做好准备。其次，经 IRB 和执行委员会批准的单独研究项目可以使用数据进行痴呆症研究。 根据 HIPAA，仅向经批准的单独项目提供最低限度的必要数据。第三，数据还将存储在国家阿尔茨海默病协调中心（美国国立卫生研究院资助的中心）的国家数据库中。发送给 NACC 的数据不包含姓名、医疗记录号或社会保险号