SOUTHWEST ONCOLOGY GROUP STATISTICAL CENTER

西南肿瘤集团统计中心

• 批准号: 8054802
• 负责人: JOHN J CROWLEY
• 金额: $ 460.4万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8054802
• 关键词: Address; Adult; Cancer Control Research; Cancer Survivor; Caring; Clinical Research Associate; Clinical Trials; Collaborations; Collection; Computer software; Conduct Clinical Trials; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Development; Electronics; Eligibility Determination; Ensure; Evaluation; Experimental Designs; Future; Goals; Guidelines; Institution; Maintenance; Malignant Neoplasms; Methods; Mission; Monitor; Nurses; Oncologist; Online Systems; Patients; Performance; Phase; Probability; Procedures; Process; Protocols documentation; Publications; Quality Control; Quality of life; Randomized; Research; Research Design; Research Personnel; Research Support; Resources; Role; Sample Size; Scientific Advances and Accomplishments; Southwest Oncology Group; Survival Analysis; Training; cancer therapy; data integrity; data management; design; improved; longitudinal analysis; meetings; oncology; operation; prevent; protocol development; sound; statistical center; statistics; therapy outcome; translational study

DESCRIPTION (Provided by applicant): The mission of the Southwest Oncology Group (SWOG) is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The mission is accomplished through the mutual efforts ofthe Group Chair's Office, the Operations Office, the Statistical Center and the dedicated oncology professionals in the institutions of the Group. The Statistical Center contributes to the mission of the Group though the following key activities: 1) Participation in protocol development, emphasizing statistically sound study designs; 2) Collection, review, manage and store data from Group studies, and to follow sound quality control procedures which ensure the integrity of data evaluations; 3) Development and maintenance of electronic applications to support the research and goals of the Southwest Oncology Group, including data collection, data management, data retrieval and analysis; 4) Analysis, interpretation and publication of results from ail Southwest Oncology Group studies; 5) Performance of methodologic research to address ongoing design and analysis issues important to the conduct of cancer clinical trials and to ancillary biologic studies; 6) Participation in training of new Clinical Research Associates (CRAs) and of Young Investigators in the Group. Biostatisticians and Data Coordinators educate investigators, nurse oncologists and CRAs in statistical analysis, research design and the utilization of the most advanced scientific and data management strategies; and 7) Collaboration with the Group Chair and other investigators in the Group to improve the quality of clinical trials through the use of improved data collection forms, reproducible data definitions and economical data flow, and efficient use of Statistical Center resources.

描述（由申请人提供）：西南肿瘤学组（SWOG）的任务是进行临床试验，以预防和治疗成人的癌症，并改善癌症幸存者的生活质量。该任务是通过集团主席办公室，运营办公室，统计中心以及该机构机构的专门肿瘤专业人士的共同努力来完成的。统计中心通过以下关键活动为小组的任务做出了贡献：1）参与协议开发，强调统计上合理的研究设计； 2）从小组研究中收集，审查，管理和存储数据，并遵循确保数据评估完整性的声音质量控制程序； 3）开发和维护电子应用程序，以支持西南肿瘤学小组的研究和目标，包括数据收集，数据管理，数据检索和分析； 4）分析，解释和发布西南肿瘤学小组研究的结果； 5）方法学研究的表现，以解决正在进行的设计和分析问题对癌症临床试验和辅助生物学研究重要的重要性； 6）参与该小组的新临床研究助理（CRA）和年轻研究人员的培训。生物统计学家和数据协调员在统计分析，研究设计以及最先进的科学和数据管理策略的利用中教育研究人员，护士肿瘤学家和CRA； 7）与小组中的小组主席和其他研究人员合作，通过使用改进的数据收集表，可重复可重复的数据定义和经济数据流以及有效利用统计中心资源来提高临床试验的质量。