SOUTHWEST ONCOLOGY GROUP STAISTICAL CENTER

西南肿瘤集团统计中心

• 批准号: 3558234
• 负责人: JOHN J CROWLEY
• 金额: $ 112.89万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-01-01 至 1987-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3558234
• 关键词: cooperative study; human subject; neoplasm /cancer epidemiology; online computer

This proposal describes how the Southwest Oncology Group Statistical Center would be organized and operated to provide data management and evaluation, statistical analysis, and input on design of protocols for clinical trials in cancer. It is proposed to locate the Statistical Center at the Fred Hutchinson Cancer Research Center in Seattle, Washington, under the direction of Dr. John Crowley, with Dr. Brent Blumenstein as Deputy Director. The application concentrates on the role of the Statistical Center in developing and monitoring protocols, including eligibility criteria, registration and randomization procedures, endpoint and sample size determination, trial monitoring, and analysis strategies. Data management and database management strategies are described in detail. Transition plans and plans for the future are also discussed.

该建议描述了西南肿瘤学集团统计中心如何 将组织和操作以提供数据管理和评估， 统计分析和临床试验方案设计的输入 在癌症中。 提议将统计中心定位在弗雷德 华盛顿西雅图的哈钦森癌症研究中心 约翰·克劳利（John Crowley）博士的指导，布伦特·布鲁门斯坦（Brent Blumenstein）博士担任副手 导演。 申请集中于统计的作用 中心开发和监视协议，包括资格 标准，注册和随机过程，端点和样本 大小确定，试用监测和分析策略。 数据 管理和数据库管理策略将详细描述。 还讨论了未来的过渡计划和计划。