An Innovative Endoscopic Instrument with Full-Field Viewing and Intelligent Imagi

具有全视野和智能成像的创新内窥镜仪器

• 批准号: 7921222
• 负责人: Steven Yi
• 金额: $ 14.74万
• 依托单位: ALTRUM TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2010-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7921222
• 关键词: Accounting; Affect; Aging; Area; Arizona; Arthroscopy; Chronically Ill; Clinic; Colon; Colonoscopy; Computer software; Cystoscopes; Cystoscopy; Diagnosis; Digestive System Disorders; Disease; Distal; Documentation; Early Diagnosis; Endoscopes; Endoscopy; Equipment; Esophagus; Fiber Optics; Gases; Gastrointestinal tract structure; Gastroscopes; Growth; Gynecology; Hand; Image; Imaging Techniques; Industry; Laparoscopy; Legal patent; Lighting; Maintenance; Marketing; Medical; Methods; Motion; Neuroendoscopy; Neurology; Nurses; Office Visits; Operative Surgical Procedures; Optics; Patients; Performance; Phase; Population; Prevention; Procedures; Process; Publishing; Rectum; Reporting; Research; Robotics; Security; Small Business Innovation Research Grant; Small Intestines; Solid; Staging; Stomach; System; Techniques; Technology; Testing; Time; Training; Tube; United States; Urology; Water; Work; base; cancer site; clinical Diagnosis; commercialization; cost; design; disease diagnosis; disorder prevention; economic impact; flexibility; image registration; improved; innovation; instrument; lens; minimally invasive; next generation; novel; optical imaging; programs; prototype; public health relevance; rapid diagnosis; research study; retinal rods; sensor; simulation; software systems; tool; visual information

DESCRIPTION (provided by applicant): The National Digestive Diseases Information Clearinghouse (NDDIC) estimates that between 60 and 70 million people in the US are affected by digestive diseases each year. Annually, diseases of the GI tract account for more than 30 million office visits and more than 10 million GI endoscopic procedures in the United States alone for the examinations of digestive tract including the esophagus, stomach, small intestine, colon, and rectum. The associated national cost is over $60 billion per year. Aside from early stage prevention, effective, low cost, and comfortable early diagnosis technologies are in great need to improve the situation. Traditional minimally invasive endoscopies still have major structural design drawbacks causing significant discomfort and billions of dollars' more to the patients. Built on our patent pending 360 degree imaging optics, with unique image unwarping and robust panoramic stabilization techniques, our proposed system will have the following clinic impact and significance: A minimally invasive and effective 360 degrees viewing video endoscopy: In addition to the traditional forward looking view, our equipment offers instant 360 degrees viewing images mechanically free, there is no need to bend the tip any more. No missing GI disorder areas: Our equipment offers a complete 360 degrees surrounding of the GI tract, no area will be missed. Accurate and rapid diagnosis: Through more effective image registration and stabilization, System SW is expected to help GI doctors/nurses to rapidly (expected by a factor of 3) and accurately diagnose abnormalities. .. "Chip-on-the-tip" low cost system for better mass acceptance and effective disease prevention: Due to its unique structural and optical design, we expect total system cost around $300. Expandable and scalable technology: The proprietary omni-directional technology developed can be easily applied to existing diagnosis instruments (endoscopes, colonscope, gastroscope, etc) to provide similar benefits to the patients The research report published by Global Markets Direct finds that, driven by the increasing number of the chronically ill population and aging, the U.S. flexible endoscope market valued at $693 million in 2008 is forecast to grow by 7.7% annually during 2008-2015 to reach $1.1 billion by 2015. The market of the rigid endoscopes (e.g. laparoscopy, urology and arthroscopy) is slightly smaller than flexible endoscopes, but with similar market growth rate. Global market is approaching $10 billion. With the advance of the emerging economies, the global endoscope demand is expected to grow with an increased rate. The commercialization potential and economic impact of the proposed system and technology is thus significant. PUBLIC HEALTH RELEVANCE: The endoscopy system and technology developed under this SBIR project will provide great benefit to GI patients by providing a low cost and minimally invasive method for early GI tract disease diagnosis and prevention. The proposed system provides an innovative panoramic imaging and traditional forward looking imaging technique leading to less discomfort to patients, much shorter diagnosis time yet with more accurate results. With the extended capability over current endoscopes, proposed system is expected to have a reasonably large market share of this 10 billion dollar industry. Other medical areas benefitting from this research include urology, neurology, gynecology, arthroscopy etc. for the next generation cystoscopy, neuroendoscopy, laparoscopy, etc. Non-medical fields to benefit this technology include commercial perimeter surveillance, and water and gas pipe inspection - another multi-billion market.

描述（由申请人提供）：国家消化系统疾病信息交换所 (NDDIC) 估计，美国每年有 60 至 7000 万人受到消化系统疾病的影响。仅在美国，每年因胃肠道疾病就诊的人数就超过 3000 万人次，接受胃肠道内窥镜检查的人数也超过 1000 万次，用于检查消化道，包括食道、胃、小肠、结肠和直肠。每年相关的国家成本超过 600 亿美元。除了早期预防外，还非常需要有效、低成本、舒适的早期诊断技术来改善这种情况。传统的微创内窥镜仍然存在重大的结构设计缺陷，导致患者明显不适并造成数十亿美元的损失。我们提出的系统基于我们正在申请专利的 360 度成像光学器件，具有独特的图像矫正和强大的全景稳定技术，将具有以下临床影响和意义： 微创且有效的 360 度观看视频内窥镜：除了传统的前瞻性视图，我们的设备提供即时 360 度观看图像，无需机械操作，无需再弯曲尖端。无遗漏胃肠道紊乱区域：我们的设备提供完整的 360 度胃肠道环绕，不会遗漏任何区域。 准确快速的诊断：通过更有效的图像配准和稳定，System SW有望帮助胃肠道医生/护士快速（预期为3倍）并准确地诊断异常情况。 ..“尖端芯片”低成本系统，可提高大众接受度并有效预防疾病：由于其独特的结构和光学设计，我们预计系统总成本约为 300 美元。可扩展和可扩展的技术：所开发的专有全向技术可以轻松应用于现有的诊断仪器（内窥镜、结肠镜、胃镜等），为患者提供类似的好处 Global Markets Direct 发布的研究报告发现，在随着慢性病人口数量的增加和老龄化，美国柔性内窥镜市场 2008 年价值 6.93 亿美元，预计 2008-2015 年每年增长 7.7%，达到到2015年将达到11亿美元。硬性内窥镜（例如腹腔镜、泌尿外科和关节镜）的市场略小于柔性内窥镜，但市场增长率相似。全球市场接近100亿美元。随着新兴经济体的进步，全球内窥镜需求预计将加速增长。因此，所提出的系统和技术的商业化潜力和经济影响是巨大的。 公共健康相关性：该 SBIR 项目开发的内窥镜系统和技术将为胃肠道疾病的早期诊断和预防提供低成本、微创的方法，从而为胃肠道患者带来巨大利益。该系统提供了创新的全景成像和传统的前视成像技术，可以减少患者的不适，缩短诊断时间，同时获得更准确的结果。凭借现有内窥镜的扩展功能，所提出的系统预计将在这个价值 100 亿美元的行业中占据相当大的市场份额。受益于这项研究的其他医学领域包括泌尿科、神经科、妇科、关节镜检查等下一代膀胱镜检查、神经内窥镜检查、腹腔镜检查等。受益于这项技术的非医学领域包括商业周界监控以及水和煤气管道检查——另一个数十亿的市场。