CLINICAL TRIAL: PACTG 1058:INTENSIVE PHARMACOKINETIC STUDIES OF ANTIRETROVIRAL D

临床试验：PACTG 1058：抗逆转录病毒 D 的强化药代动力学研究

• 批准号: 7951157
• 负责人: DOUGLAS WATSON
• 金额: $ 0.53万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951157
• 关键词: Adolescent; Adult; Affect; Anti-Retroviral Agents; Child; Clinical Research; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Drug Kinetics; Drug usage; Funding; Grant; HIV; HIV Infections; Hour; Institution; Pharmaceutical Preparations; Research; Research Personnel; Resources; Source; United States National Institutes of Health; interest

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Treating HIV infection requires combinations of at least 3, and often many more drugs. Several of the drugs used to treat HIV affect how the body eliminates other HIV drugs. Many of these interactions have been studied in adults, but far less is known about their use in children and adolescents. This study will look at the level of HIV drugs over a 12-hour period in children and adolescents who have been prescribed one of three combinations of HIV drugs of interest. This information will help doctors decide how much drug they should prescribe.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 治疗 HIV 感染需要至少 3 种药物（通常是更多药物）的组合。用于治疗艾滋病毒的几种药物会影响身体消除其他艾滋病毒药物的方式。其中许多相互作用已在成​​人中进行了研究，但对其在儿童和青少年中的使用知之甚少。这项研究将考察儿童和青少年在 12 小时内的 HIV 药物水平，这些儿童和青少年服用了三种感兴趣的 HIV 药物组合中的一种。这些信息将帮助医生决定应该开多少药。