CLINICAL TRIAL: PACTG 1058:INTENSIVE PHARMACOKINETIC STUDIES OF ANTIRETROVIRAL D

临床试验：PACTG 1058：抗逆转录病毒 D 的强化药代动力学研究

• 批准号: 7951157
• 负责人: DOUGLAS WATSON
• 金额: $ 0.53万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951157
• 关键词: Adolescent; Adult; Affect; Anti-Retroviral Agents; Child; Clinical Research; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Drug Kinetics; Drug usage; Funding; Grant; HIV; HIV Infections; Hour; Institution; Pharmaceutical Preparations; Research; Research Personnel; Resources; Source; United States National Institutes of Health; interest

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Treating HIV infection requires combinations of at least 3, and often many more drugs. Several of the drugs used to treat HIV affect how the body eliminates other HIV drugs. Many of these interactions have been studied in adults, but far less is known about their use in children and adolescents. This study will look at the level of HIV drugs over a 12-hour period in children and adolescents who have been prescribed one of three combinations of HIV drugs of interest. This information will help doctors decide how much drug they should prescribe.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 治疗艾滋病毒感染需要至少3种，而且通常更多的药物。用于治疗HIV的几种药物会影响人体消除其他HIV药物的方式。这些相互作用中的许多已经在成人中进行了研究，但是对他们在儿童和青少年中的使用知之甚少。这项研究将考虑在12小时内的儿童和青少年的艾滋病毒药物水平，这些儿童和青少年被开处方了感兴趣的艾滋病毒药物的三种组合之一。这些信息将帮助医生确定他们应该开的药物。