Pilot Project Program
试点项目计划
基本信息
- 批准号:9918116
- 负责人:
- 金额:$ 18.46万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-05-22 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAreaAwardBasic ScienceBiomedical ResearchCaliforniaClinicalClinical ResearchCollaborationsCommunitiesCommunity HealthCore FacilityDevelopmentEnsureEnvironmental HealthEpidemiologyEvaluationFacultyFeedbackFosteringFundingFunding OpportunitiesFutureGoalsGrantHealthInstitutionInterdisciplinary StudyLinkMentorsMentorshipMissionNational Institute of Environmental Health SciencesOutcomePilot ProjectsPlanet EarthPopulationProcessProfessional PracticeReportingReproductionRequest for ApplicationsResearchResearch PersonnelResearch Project GrantsResource AllocationResourcesSan FranciscoScientistSeedsSiteTimeTransferable SkillsTranslational ResearchTranslationsUnited States National Institutes of HealthUniversitiesWorkbasecareercareer developmentepidemiology studyexperienceinnovationinterdisciplinary approachmembermultidisciplinarynext generationnovelprogramsskill acquisitionsuccess
项目摘要
ABSTRACT – PILOT PROJECT PROGRAM
The University of California, San Francisco (UCSF) Environmental Research and Translation for Health
(EaRTH) Center offers the unique opportunity to support and grow an environmental health community at a
premier multidisciplinary biomedical research institution with nearly 5,000 faculty members with expertise
spanning basic, translational, clinical, and population arenas. Despite being the top NIH-funded public university,
only 0.7% of NIH funding at UCSF currently comes from NIEHS. The EaRTH Center Pilot Project Program
provides a mechanism to increase the amount of environmental health research at UCSF by tapping into the
existing broad research base. By providing seed funds for exploratory studies, EaRTH Pilot Project awards will
lower hurdles to initiating novel directions in environmental research and grow the pipeline of researchers and
clinicians in environmental health. We will support the mission of the EaRTH Center by enabling cutting edge,
exploratory research in areas directly related to environmental health. This goal is promoted by supporting basic,
translational, epidemiological and clinical research projects through Core facilities as well as providing interaction
with a community of researchers through the EaRTH Center. A Research Pilot Award will allow new or
established faculty to rapidly transfer skills and developments from other research areas to the arena of
environmental health research. A Mentored Scientist Award specifically for early-stage investigators will
support innovative research projects and provide career and mentoring in environmental health research. A
Mentored Clinician Award, administered jointly with the Community Engagement Core (CEC), for clinicians will
provide dedicated time for a clinician to gain experience in environmental health. The Pilot Project Program will
stimulate research that fills gaps in the area of environmental health in development and preconception at UCSF.
To streamline the application process and to capture the largest number of high quality applications with
innovative projects proposed from researchers outside of environmental health, we will conduct the RFA through
the broadly used UCSF Resource Allocation Program (RAP). Evaluation metrics will be applied to the pilot
projects to assess and promote success of projects and the overall program. The UCSF EaRTH Center
engagement with the entire UCSF scientific community will enable discussions of the application of
interdisciplinary approaches to environmental health research. This ensures our pilot grant recipients have full
access to local expertise, which assists their entry into, and staying power in, environmental health-related areas.
摘要 – 试点项目计划
加州大学旧金山分校 (UCSF) 健康环境研究与转化
(EaRTH) 中心提供了独特的机会来支持和发展环境健康社区
首屈一指的多学科生物医学研究机构,拥有近 5,000 名具有专业知识的教职员工
尽管是美国国立卫生研究院 (NIH) 资助的顶尖公立大学,但它涵盖基础、转化、临床和人口领域。
目前 UCSF 的 NIH 资金中只有 0.7% 来自 NIEHS 地球中心试点项目计划。
提供了一种机制,通过利用
通过为探索性研究提供种子资金,EaRTH 试点项目将授予现有广泛的研究基础。
降低环境研究新方向的障碍,扩大研究人员队伍
我们将通过支持尖端技术来支持地球中心的使命。
通过支持基础的、与环境健康直接相关的领域的探索性研究来促进这一目标。
通过核心设施开展转化、流行病学和临床研究项目并提供互动
通过地球中心的研究试点奖将允许新的或
建立教师队伍是为了将其他研究领域的技能和发展迅速转移到
环境健康研究将获得专门针对早期研究人员的导师科学家奖。
支持创新研究项目并提供环境健康研究方面的职业和指导。
指导临床医生奖,与社区参与核心 (CEC) 联合管理,奖励信徒
试点项目计划将为临床医生提供专门的时间来获得环境健康方面的经验。
刺激研究,填补加州大学旧金山分校环境健康领域发展和先入为主的空白。
简化申请流程并获取最大数量的高质量申请
环境健康以外的研究人员提出的创新项目,我们将通过以下方式进行 RFA:
广泛使用的 UCSF 资源分配计划 (RAP) 评估指标将应用于试点。
评估和促进项目和整体计划成功的项目。
整个加州大学旧金山分校科学界的参与将有助于讨论
跨学科方法进行环境健康研究,这确保了我们的试点资助获得者能够充分利用这些方法。
获得当地的专业知识,这有助于他们进入环境健康相关领域并保持活力。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Diana J Laird其他文献
Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions.
TET1 的迭代氧化对于印记控制区域的重编程和小鼠精子低甲基化区域的图案化是必需的。
- DOI:
10.1016/j.devcel.2024.02.012 - 发表时间:
2024-04-01 - 期刊:
- 影响因子:11.8
- 作者:
Rexxi D. Prasasya;Blake A. Caldwell;Zhengfeng Liu;Songze Wu;N. A. Leu;Johanna M. Fowler;Steven A Cincotta;Diana J Laird;Rahul M Kohli;Marisa S Bartolomei - 通讯作者:
Marisa S Bartolomei
Transcriptional repression upon S phase entry protects genome integrity in pluripotent cells
进入 S 期时的转录抑制可保护多能细胞的基因组完整性
- DOI:
10.1038/s41594-023-01092-7 - 发表时间:
2023-09-11 - 期刊:
- 影响因子:16.8
- 作者:
Deniz Gökbuget;Kayla Lenshoek;Ryan M. Boileau;Jonathan Bayerl;Hector Huang;A. Wiita;Diana J Laird;R. Blelloch - 通讯作者:
R. Blelloch
Diana J Laird的其他文献
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{{ truncateString('Diana J Laird', 18)}}的其他基金
The intersection of stress and environmental chemicals in germ cell reprogramming
生殖细胞重编程中压力和环境化学物质的交叉点
- 批准号:
10350839 - 财政年份:2021
- 资助金额:
$ 18.46万 - 项目类别:
The intersection of stress and environmental chemicals in germ cell reprogramming
生殖细胞重编程中压力和环境化学物质的交叉点
- 批准号:
9762104 - 财政年份:2017
- 资助金额:
$ 18.46万 - 项目类别:
Fmr1 Function and Repeat Expansion in the Developing Germline
发育中种系中的 Fmr1 功能和重复扩增
- 批准号:
10065433 - 财政年份:2017
- 资助金额:
$ 18.46万 - 项目类别:
The intersection of stress and environmental chemicals in germ cell reprogramming
生殖细胞重编程中压力和环境化学物质的交叉点
- 批准号:
10463110 - 财政年份:2017
- 资助金额:
$ 18.46万 - 项目类别:
The intersection of stress and environmental chemicals in germ cell reprogramming
生殖细胞重编程中压力和环境化学物质的交叉点
- 批准号:
10245162 - 财政年份:2017
- 资助金额:
$ 18.46万 - 项目类别:
Assessing transgenerational effects of Phthalates on primordial germ cells
评估邻苯二甲酸盐对原始生殖细胞的跨代影响
- 批准号:
8599113 - 财政年份:2013
- 资助金额:
$ 18.46万 - 项目类别:
Assessing transgenerational effects of Phthalates on primordial germ cells
评估邻苯二甲酸盐对原始生殖细胞的跨代影响
- 批准号:
8728236 - 财政年份:2013
- 资助金额:
$ 18.46万 - 项目类别:
Cell competition in the developing mouse germline
发育中的小鼠种系中的细胞竞争
- 批准号:
7981845 - 财政年份:2010
- 资助金额:
$ 18.46万 - 项目类别:
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