NEUROCOGNITIVE PROGNOSIS IN SURVIVORS OF BRAIN TUMORS

脑肿瘤幸存者的神经认知预后

• 批准号: 7951249
• 负责人: ELANA FARACE
• 金额: $ 0.28万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951249
• 关键词: Brain Neoplasms; Cancer Patient; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Equation; Funding; Goals; Grant; Impaired cognition; Institution; Length; Malignant neoplasm of brain; Modeling; Neurocognitive; Patients; Population; Quality of life; Research; Research Personnel; Resources; Source; Survivors; Testing; Time; United States National Institutes of Health; end of life; improved; neuro-oncology; neuropsychological; outcome forecast; patient population; survivorship

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The central tenet of the proposed research is that including neuropsychological variables can improve understanding of patients' QOL, elucidate QOL trajectory to end-of-life, and help predict length of survival in malignant brain tumor patient populations. In order to test this proposal, structural equation modeling will be performed to determine inter-relationships of components of QOL, their trajectory over time, and the extent to which QOL predicts patient survival. Results will have implications not only for neuro-oncology, but also for all cancer patients with cognitive impairment, contributing to improved QOL and survivorship for these populations. The ultimate goal is to maximize both survival and QOL.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 拟议的研究的核心宗旨是，包括神经心理学变量可以提高对患者QOL的理解，阐明QOL轨迹到寿命末，并有助于预测恶性脑肿瘤患者人群的生存时间。为了测试该建议，将进行结构方程建模，以确定QOL组成部分的相互关联，它们的轨迹随着时间的推移以及QOL预测患者存活的程度。结果不仅对神经肿瘤学有影响，而且对所有认知障碍的癌症患者也有影响，这有助于改善这些人群的QOL和生存。最终目标是最大化生存和QoL。