The Effect of a School Based Hand Sanitizer Program on Asthma

学校洗手液计划对哮喘的影响

• 批准号: 7840354
• 负责人: WILLIAM C BAILEY
• 金额: $ 69.6万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7840354
• 关键词: Asthma; Child; Childhood Asthma; Crossover Design; Effectiveness; Environment; Hand; Hand functions; Handwashing; Health Care Costs; Hygiene; Internet; Intervention; Measures; Monitor; Morbidity - disease rate; Pharmaceutical Preparations; Placebos; Public Health; Randomized; Reading; Research; Risk; School-Age Population; Schools; Soaps; Symptoms; System; Time; United States; Viral Respiratory Tract Infection; Virus; Virus Diseases; Water; age related; antimicrobial; base; combat; improved; meter; prevent; programs

DESCRIPTION (provided by applicant): Pediatric asthma is a well documented public health issue in the United States. The impact of pediatric asthma can be measured by both health care costs and morbidity. Asthma morbidity is seasonal with the greatest number of exacerbations occurring in autumn and the fewest in mid-summer. There is a strong age-related seasonal variability with grade school children being the most vulnerable to seasonal changes. Furthermore, the annual peak asthma morbidity for children has been shown to be associated with the start of the school year. Recent research suggests that this seasonality in children is primarily related to viral respiratory tract infections. Regular handwashing has been widely recognized as the most effective means to combat the spread of infectious illness, including viruses. However, effective handwashing among school-age children is inconsistent at best. The school setting provides multiple barriers to effective handwashing such as time constraints, and frequent lack of soap, towels, and strategically located sinks. Spring loaded faucets which serve to prevent overuse of water inadvertently pose an additional barrier to thorough hand cleansing. Hand sanitization in such settings may be effectively accomplished by antimicrobial rinse-free hand sanitizers. Therefore, we propose to collaborate with a single school district to achieve the following specific aims: 1. Develop a simple school based intervention using hand sanitizers to decrease asthma exacerbations in children with asthma. 2. Implement a school based internet monitoring system within both the active and placebo groups to record asthma symptoms, peak flow meter readings, school absences, and use of rescue medications at school. 3. Randomize 26 schools to either active or placebo hand sanitizer. 4. Use a cross-over design to compare the active and placebo groups with regard to time-averaged proportion of children with asthma who have at least one exacerbation per month. Improving hand hygiene in the school environment may be a relatively simple, yet effective way to reduce the risk of asthma exacerbations. By achieving these specific aims, this study will provide valuable information on the effectiveness of hand sanitizers in the school setting.

描述（由申请人提供）：小儿哮喘是美国有据可查的公共卫生问题。小儿哮喘的影响可以通过医疗保健成本和发病率来衡量。哮喘发病率是季节性的，秋季发生的加重最多，仲夏最少。与年龄相关的季节性差异很强，小学生最容易受到季节性变化的影响。此外，儿童的年度哮喘发病率已被证明与学年的开始有关。最近的研究表明，儿童的这种季节性主要与病毒呼吸道感染有关。定期洗手已被广泛认为是打击传染病（包括病毒）的最有效手段。但是，在学龄儿童中进行有效的洗手充其量是不一致的。学校环境为有效的洗手提供了多个障碍，例如时间限制，经常缺乏肥皂，毛巾和策略性的水槽。春季装载的水龙头可防止过度使用水，构成了额外的障碍，以彻底清洁。在这种环境中的手动消毒可以通过无抗菌冲洗式洗手液有效地完成。因此，我们建议与单个学区合作，以实现以下特定目标：1。使用手动消毒剂制定基于学校的简单干预措施，以减少患有哮喘儿童的哮喘患者。 2。在活动和安慰剂组中实施基于学校的互联网监测系统，以记录哮喘症状，峰值流量计读数，学校缺席以及在学校使用救援药物。 3。将26所学校随机进行活跃或安慰剂洗手液。 4.使用跨界设计比较了活跃的和安慰剂组，与每月至少有一种加重的哮喘儿童的时间平均比例。改善学校环境中的手卫生可能是一种相对简单但有效的方法来降低哮喘加重的风险。通过实现这些特定目标，这项研究将提供有关手动消毒剂在学校环境中有效性的宝贵信息。