A Skin Cancer Prevention Video Intervention for Organ Transplant Recipients

针对器官移植受者的皮肤癌预防视频干预

基本信息

批准号：
7941077
负责人：
LOIS J LOESCHER
金额：
$ 7.47万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-29 至 2012-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7941077
关键词：
Address Affect Attitude Basal Cell Cancer Behavior Behavior Control Behavioral Cancer Detection Cessation of life Cicatrix Clinic Clinical Cosmetics Detection Development Early Diagnosis Funding General Population Goals Health Personnel Heart Immune system Immunosuppression Intention Intervention Kidney Knowledge Life Liver Longevity Lung Malignant Neoplasms Malignant Squamous Cell Neoplasm Methodology Methods Modeling Morbidity - disease rate Neoplasm Metastasis Organ Organ Transplantation Outcome Outpatients Pamphlets Pancreas Patient Self-Report Personal Behavior Persons Pharmacotherapy Physicians Play Prevention Recurrence Research Risk Role Screening for Skin Cancer Self Efficacy Self-Examination Skin Skin Cancer Skin Carcinoma Solid Sun Exposure Technology Testing Therapeutic immunosuppression Time Transplant Recipients Transplantation UV Radiation Exposure United States Work Writing base behavior change cancer risk carcinogenesis comparison group evidence base high risk improved innovation melanoma mortality novel strategies post intervention programs public health relevance skin cancer prevention success sun protection tool

项目摘要

DESCRIPTION (provided by applicant): Organ transplant recipients (OTR)-persons receiving donated solid organs such as kidneys, pancreases, livers, lungs, or hearts-are at exceptionally high risk of all types of skin cancer. Increased risk likely results from immune system changes brought on by life-long drug therapy required after transplantation. Sun exposure also plays a role in development of skin cancer. More than 230,000 OTR in the U.S. are up to 250 times more likely to develop skin cancer than the general public. With the long-term success of organ transplantation improving to 90%, more OTR will be at continued risk of skin cancer. Skin cancer (squamous cell cancer, basal cell cancer, or melanoma) has serious outcomes ranging from scarring and cosmetic disfigurement to death. In OTR, skin cancer is highly aggressive and hard to treat; therefore, prevention and detection are critical for improving survival. Behaviors known to lessen skin cancer risk and improve survival of skin cancer are sun protection and skin self-examination. Unfortunately, OTR do not receive adequate information on skin cancer prevention and detection from healthcare providers. The few OTR who have received verbal or written information retain some skin cancer knowledge, but there are only two existing studies of approaches to improve skin cancer prevention/detection behaviors (sun protection, skin examination) in OTR. These approaches were verbal information from physicians and written brochures. With funding from the NCI, we will first develop a new approach: a short video to provide skin cancer prevention and detection information that is tailored to OTR. We will then compare changes in sun protection and skin self-examination behaviors in two groups of OTR (132 total) who recently underwent transplantation and are being followed in outpatient OTR clinics: (1) 66 OTR who view the video plus receive skin cancer general information brochures and (2) 66 OTR who receive the brochures only. We also will evaluate the effect of the video approach on factors known to influence behavior change, specifically attitudes toward skin cancer, intention to engage in sun protection and skin self-examination behaviors, self confidence in performing the behavior, and personal control over doing the behavior. Findings from this study will help healthcare providers to better inform OTR about their high risk of skin cancer and options for risk- reducing behaviors. Findings also will provide more information about factors that may be important in skin cancer prevention and detection behavior change. PUBLIC HEALTH RELEVANCE: Organ transplant recipients (e.g., receiving kidneys, lungs, pancreases, etc.) are at extremely high risk of skin cancer. They receive little information on skin cancer prevention and detection from healthcare providers. We will develop and evaluate a new information tool: a prevention/detection video tailored to these recipients.

描述（由申请人提供）：器官移植受者（OTR）——接受肾脏、胰腺、肝脏、肺或心脏等捐赠实体器官的人——患所有类型皮肤癌的风险极高。风险增加可能是由于移植后所需的终生药物治疗引起的免疫系统变化所致。阳光照射也在皮肤癌的发生中发挥作用。美国有超过 230,000 名 OTR 患皮肤癌的可能性是普通公众的 250 倍。随着器官移植的长期成功率提高到 90%，更多的 OTR 将持续面临皮肤癌的风险。皮肤癌（鳞状细胞癌、基底细胞癌或黑色素瘤）会产生严重的后果，包括疤痕、容貌毁容甚至死亡。在 OTR 中，皮肤癌具有高度侵袭性且难以治疗；因此，预防和检测对于提高生存率至关重要。已知可降低皮肤癌风险并提高皮肤癌生存率的行为包括防晒和皮肤自我检查。不幸的是，OTR 没有从医疗保健提供者那里获得有关皮肤癌预防和检测的足够信息。少数收到口头或书面信息的 OTR 保留了一些皮肤癌知识，但现有的关于改善 OTR 中皮肤癌预防/检测行为（防晒、皮肤检查）的方法的研究只有两项。这些方法是医生的口头信息和书面小册子。在 NCI 的资助下，我们将首先开发一种新方法：通过短视频提供专为 OTR 定制的皮肤癌预防和检测信息。然后，我们将比较最近接受移植并在门诊 OTR 诊所接受随访的两组 OTR（总共 132 名）的防晒和皮肤自我检查行为的变化：（1）66 名观看视频并接受皮肤癌一般检查的 OTR信息手册和 (2) 66 OTR 仅收到手册。我们还将评估视频方法对已知影响行为改变的因素的影响，特别是对皮肤癌的态度、参与防晒和皮肤自我检查行为的意愿、执行该行为的自信以及对执行该行为的个人控制。行为。这项研究的结果将帮助医疗保健提供者更好地告知 OTR 他们患皮肤癌的高风险以及降低风险行为的选择。研究结果还将提供更多关于可能对皮肤癌预防和检测行为改变重要的因素的信息。公众健康相关性：器官移植受者（例如接受肾脏、肺、胰腺等）患皮肤癌的风险极高。他们从医疗保健提供者那里收到的有关皮肤癌预防和检测的信息很少。我们将开发和评估一种新的信息工具：为这些接收者量身定制的预防/检测视频。