Protocol Specific Research

协议特定研究

• 批准号: 7802183
• 负责人: Victor M. Santana
• 金额: $ 17.25万
• 依托单位: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7802183
• 关键词: Applications Grants; Cancer Center; Cancer Center Support Grant; Clinical Research Associate; Clinical Trials; Developmental Therapeutics Program; Enrollment; Industry; Leadership; Nursing Research; Patients; Pediatric Oncology; Phase; Protocols documentation; Recruitment Activity; Research; Research Support; Resources; Saint Jude Children' s Research Hospital; Therapeutic; Therapeutic Clinical Trial; Therapy Clinical Trials; base; indexing; innovation; programs

CCSG support of research nurses and clinical research associates dedicated to the conduct and completion of innovative, feasibility or proof-of-principle clinical trials proposed by Cancer Center Programs is critical for SJCRH's continued contribution to pediatric oncology. The Cancer Center leadership is dedicated to protocolspecific research and only trials considered to be of the highest priority are supported by this resource. Our commitment to protocol-based research is illustrated in Summary Table 3 in section 7.0 of this grant application. That table shows that for the index year of October 1, 2005 through September 30, 2006, of 373 patients presenting to St. Jude, 247 (66%) were treated on a therapeutic clinical trial as part of their initial treatment at St. Jude. Eighty-five (85%) of these enrollments were Cancer Center protocols, with the remaining 15% on industry or national protocols. In addition, of the 247 patients enrolling on therapeutic trials during the index year, 56 (23%) were also treated on more than one trial, resulting in 312 therapeutic enrollments. This is largely a result of St. Jude's concentrated effort to recruit previously treated patients to St. Jude for our Phase l/ll Developmental Therapeutics Program. Finally, the 373 patients presenting during the index year also contributed to 549 non-therapeutic enrollments, for a total of 861 protocol enrollments during the index year.

CCSG 支持研究护士和临床研究助理致力于开展和完成 癌症中心计划提出的创新、可行性或原理验证临床试验对于 SJCRH 对儿科肿瘤学的持续贡献。癌症中心领导层致力于特定方案 该资源仅支持被认为具有最高优先级的研究和试验。我们的 本拨款第 7.0 节的汇总表 3 说明了对基于方案的研究的承诺 应用。该表显示，从 2005 年 10 月 1 日到 2006 年 9 月 30 日的索引年，共有 373 就诊于 St. Jude 的患者中，247 名 (66%) 接受了治疗性临床试验作为其初始治疗的一部分 在圣裘德接受治疗。其中八十五 (85%) 的注册是按照癌症中心协议进行的，其中 其余 15% 属于行业或国家协议。此外，在参加治疗试验的 247 名患者中 在索引年期间，56 名患者 (23%) 还接受了一项以上试验的治疗，从而产生了 312 名治疗患者 招生。这在很大程度上是圣裘德集中精力招募以前接受过治疗的患者到圣裘德的结果。 Jude，感谢我们的 l/ll 期发育治疗计划。最后，373 名就诊的患者 索引年还促成了 549 例非治疗性入组，期间总共有 861 例方案入组 指数年。