University of Michigan Comprehensive Cancer Center Support Grant

密歇根大学综合癌症中心支持补助金

• 批准号: 7498747
• 负责人: MAX S. WICHA
• 金额: $ 11.4万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7498747
• 关键词: Ambulatory Care Facilities; Award; Basic Science; Behavioral; Bioinformatics; Biometry; Breast; Cancer Center; Cancer Center Support Grant; Cellular biology; Clinical; Clinical Research; Clinical Trials; Complementary DNA; Core Facility; DNA Sequence; Development; Development Plans; Evaluation; Faculty; Flow Cytometry; Funding; Goals; Grant; Growth; Head and Neck Cancer; Health Communication; Housing; Image; Immunologic Monitoring; Intervention; Journals; Laboratory Research; Leadership; Malignant Childhood Neoplasm; Medical center; Molecular; Morphology; Prevention; Prevention program; Prostate; Proteomics; Publishing; Radiation; Recruitment Activity; Research; Research Personnel; Resources; Science; Therapeutic; Tissue Procurements; Transgenic Mice; University of Michigan Comprehensive Cancer Center; animal facility; anticancer research; cancer cell; cancer genetics; cancer research center director; experience; irradiation; leukemia/lymphoma; member; molecular imaging; programs; research and development; tumor; urologic; vector

The University of Michigan Comprehensive Cancer Center (UMCCC) requests renewal of its core grant in support of Senior Leadership, Programs, and Shared Core Facilities. A core grant to support the UMCCC was initially awarded by the NCI in 1988, with continuous funding since then. Dr. Max Wicha, the founding Director of the Cancer Center, continues to serve as Director. The Center provides an organizational framework to promote interdisciplinary cancer research through the development of defined clinical, basic, and prevention programs in cancer research and the development of shared core resources. In 1997 the center moved into a new $88 million facility which houses the center's outpatient clinics as well as many of its research laboratories. The Cancer Center has continued to experience considerable growth over this grant period with 70 new faculty recruited and an 85% increase in NCI funding. The Cancer Center's 13 research programs include the basic research programs in Cancer Genetics, Cancer Cell Biology, Molecular Therapeutics, Radiation Sciences, and Molecular Imaging. Clinical research programs include Prostate/Urological, Breast, Leukemia/Lymphoma-BMT, Gl, Childhood Cancers, and Head & Neck cancers. The prevention programs include two programs: Biomedical Prevention and Socio-Behavioral. Support is requested for a total of 16 shared core facilities. These include Clinical Trials, Biostatistics, Tissue Procurement, Tumor Imaging, DNA Sequencing, Morphology, Flow Cytometry, Experimental Irradiation, Animal Facility, Transgenic Mouse, Vector Core, Immune Monitoring, cDNA Affymetrix and Microarray and three new cores including Proteomics, Bioinformatics, and Health Communications. Funds are also requested for development, planning and evaluation, and administration to support center goals. The Medical Center has made substantial commitments to the Cancer Center of approximately $175 million. Its 285 UMCCC members receive over $82 million in research funding, including over $37 million in annual direct NCI support. The UMCCC has had a major impact on cancer research as evidenced by publishing at least 315 articles in high impact journals, placing 52% of UMCCC intervention accruals onto investigator-initiated trials and consistently ranking among the top ten Cancer Centers nationally for NCI funding over this grant period.

密歇根大学综合癌症中心（UMCCC）要求续签其核心赠款 支持高级领导，计划和共享核心设施。支持UMCCC的核心赠款 最初是由NCI于1988年授予的，此后又有了持续的资金。麦克斯·维查（Max Wicha）博士，创始人 癌症中心主任继续担任主任。该中心提供了一个组织 通过开发定义的临床，基本， 以及癌症研究中的预防计划和共享核心资源的发展。 1997年 中心搬进了一个新的8800万美元的设施，该设施设有该中心的门诊诊所以及许多 它的研究实验室。癌症中心在这方面继续经历大幅增长 授予期限为70名新教职员工，NCI资金增加了85％。癌症中心的13 研究计划包括癌症遗传学，癌细胞生物学的基础研究计划， 分子疗法，辐射科学和分子成像。临床研究计划包括 前列腺/泌尿科，乳房，白血病/淋巴瘤-BMT，GL，儿童癌和头颈部 癌症。预防计划包括两个计划：生物医学预防和社会行为。 总共要求提供16个共享核心设施。这些包括临床试验，生物统计学， 组织采购，肿瘤成像，DNA测序，形态，流式细胞仪，实验性 辐照，动物设施，转基因小鼠，载体核，免疫监测，cDNA Affymetrix和 微阵列和三个新核心，包括蛋白质组学，生物信息学和健康传播。 还要求资金进行开发，计划和评估以及管理 目标。医疗中心已经对癌症中心做出了重大承诺 1.75亿美元。它的285名UMCCC成员获得了超过8200万美元的研究资金，包括超过37美元 在年度直接NCI支持中获得百万。 UMCCC对癌症研究产生了重大影响 在高影响期刊上至少发表315篇文章证明了52％的UMCCC干预措施 应计入研究者发起的试验，并始终在十大癌症中心中排名 在本赠款期间为NCI提供资金。