INBRE: URI: CENTRALIZED RES CORE FACILITY

INBRE：URI：集中资源核心设施

基本信息

批准号：
7725142
负责人：
AFTAB J AHMED
金额：
$ 21.77万
依托单位：
UNIVERSITY OF RHODE ISLAND
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-05-01 至 2009-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7725142
关键词：
Biomedical Research Charge Collaborations Communities Computer Retrieval of Information on Scientific Projects Database Computer software Core Facility DNA Educational process of instructing Educational workshop Electrophoresis Equipment Faculty Fee-for-Service Plans Fees Frequencies Funding Gene Silencing Grant Hybrids Institution Laboratories Manufacturer Name MicroRNAs Participant Pharmaceutical Preparations Pharmacy facility Polymerase Chain Reaction Postdoctoral Fellow Printing Proteins Research Research Personnel Research Project Grants Research Training Resources Rhode Island Services Small Interfering RNA Source Students System Techniques Technology Time Training Training Support United States National Institutes of Health college concept cost instrument liquid chromatography mass spectrometry novel posters theories tool

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Centralized Research Core Facility is in its fifth year of providing research and training support to the RI-INBRE participants and the Rhode Island biomedical research community. During the current year more than fifty three research groups used the facility, with an average frequency of approximately 1106 total usages per quarter. The Facility users consisted of 12 faculty, 17 postdoctoral fellows, 57 graduate students, and 29 undergraduate students. The Core Facility staff trained all new users in utilizing various technologies for their research projects. The Facility staff also participated in teaching various techniques in the undergraduate and graduate laboratory courses offered by the College of Pharmacy. In addition, several instructional seminars and training workshops were organized in collaboration with the instrument manufacturers. This year, the topics included the following: Novel TaqMan Array and microRNA Research Tools; Gene Silencing with siRNA and miRNA; New Concepts in Real Time PCR; Electrophoresis 2DE and 2D-DIGE: Theory and Practice; and Fast and Efficient Extraction of DNA, RNA, Proteins and Drugs. A QSTAR Elite Hybrid LC/MS/MS System was purchased to replace the Mariner LC/MS System. Also, the software for the Bioanalyzer System was upgrade. The Core Facility equipment and resources continue to remain available to researchers from the RI-INBRE partner institutions. No user fees were charged for equipment usage as all participating institutions contributed funds toward maintaining the Facility. This year, the poster printing service printed 268 posters for various investigators. A fee for this service will be implemented soon to recover the cost of consumables. Overall, the usage of the Core Facility continues to increase.

该子项目是利用该技术的众多研究子项目之一资源由 NIH/NCRR 资助的中心拨款提供。子项目及研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金，因此可以在其他 CRISP 条目中表示。列出的机构是对于中心来说，它不一定是研究者的机构。集中研究核心设施为 RI-INBRE 参与者和罗德岛生物医学研究界提供研究和培训支持已进入第五个年头。今年，超过 53 个研究小组使用了该设施，平均每季度总使用次数约为 1106 次。该设施的用户包括 12 名教职人员、17 名博士后研究员、57 名研究生和 29 名本科生。核心设施工作人员培训所有新用户如何利用各种技术进行他们的研究项目。设施工作人员还参与了药学院提供的本科生和研究生实验室课程的各种技术教学。此外，还与仪器制造商合作组织了多次教学研讨会和培训讲习班。今年的主题包括：新型 TaqMan 阵列和 microRNA 研究工具；使用 siRNA 和 miRNA 进行基因沉默；实时荧光定量PCR的新概念；电泳 2DE 和 2D-DIGE：理论与实践；快速有效地提取 DNA、RNA、蛋白质和药物。购买了 QSTAR Elite 混合 LC/MS/MS 系统来替换 Mariner LC/MS 系统。此外，生物分析仪系统的软件也进行了升级。 RI-INBRE 合作机构的研究人员仍可继续使用核心设施设备和资源。由于所有参与机构都为维护该设施提供资金，因此不收取设备使用费。今年，海报印刷服务为各类调查人员印刷了268张海报。这项服务即将实行收费，以收回耗材成本。总体而言，核心设施的使用率持续增加。