MOLECULAR MESSENGERS THAT UNDERLIE NEUROTOXIC AND OTHER ACTIONS OF DRUGS OF ABUSE

滥用药物产生神经毒作用和其他作用的分子信使

• 批准号: 7286939
• 负责人: SOLOMON H. SNYDER
• 金额: $ 137.63万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7286939
• 关键词: Acetylesterase; Area; Bilirubin; Biliverdin reductase; Binding; Brain; Calcium; Calmodulin; Cell Death; Cells; Corpus striatum structure; Cyclic AMP-Dependent Protein Kinases; Cytosol; D Aspartate; EP300 gene; Glucocorticoids; Glutamates; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Heme; Histone Deacetylase; Investigation; Iron; Knockout Mice; Link; Lipids; Localized; Mediating; Mediator of activation protein; Membrane; Molecular; Mus; N-Methyl-D-Aspartate Receptors; N-Methylaspartate; Neuromodulator; Neurons; Nicotinamide adenine dinucleotide; Nitric Oxide; Nuclear Translocation; Oxygenases; PTGS2 gene; Phosphorylation; Physiological; Play; Process; Progress Reports; Property; Prostaglandins; Proteins; Receptor Activation; Regulation; Research; Role; SLC11A2 gene; Scaffolding Protein; Signal Transduction; Stress; System; TP53 gene; Thyroid Hormones; base; cellular longevity; cyclooxygenase 2; drug of abuse; heme oxygenase-2; neuroprotection; neurotoxic; neurotoxicity; novel; oxidation; transmission process; uptake