2022 Chemistry and Biology of Tetrapyrroles Gordon Research Conference

2022年四吡咯化学与生物学戈登研究会议

基本信息

批准号：
10527747
负责人：
Amy Elizabeth Medlock
金额：
$ 0.85万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-07 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10527747
关键词：
Address Allergic Allergic Disease Anabolism Anemia Applied Research Area Bacteria Basic Science Bilin Bilirubin Biliverdine Biological Biology Cardiology Catalysis Cell physiology Chemicals Chemistry Chlorophyll Clinical Cobalamin Collaborations Communicable Diseases Development Disease Environment Erythropoiesis Female Fostering Goals Harvest Health Heart Diseases Hematology Heme Hepatology Homeostasis Hour Human Immune System Diseases Immunity Immunologics Immunology Individual International Iron Kidney Diseases Lead Light Liver diseases Metabolism Mission National Heart, Lung, and Blood Institute National Institute of Allergy and Infectious Disease National Institute of Diabetes and Digestive and Kidney Diseases Nephrology Neurologic Nutrient Nutritional Ointments Oral Organism Participant Pathogenesis Pigments Play Porphyrias Process Proteins Raven Reactive Oxygen Species Recording of previous events Regulation Reperfusion Injury Research Research Personnel Respiration Rhode Island Role SARS-CoV-2 infection Science Scientist Senior Scientist Signal Transduction Signaling Molecule Source Techniques Tetrapyrroles Training Underrepresented Minority United States National Institutes of Health Universities Vitamin B 12 Work absorption carbon fixation cellular development cofactor detoxication disability diversity and equity experience informal atmosphere interest meetings microbial mid-career faculty nervous system disorder next generation nutrition pathogenic microbe posters prevent professor symposium trafficking

项目摘要

PROJECT SUMMARY The Chemistry and Biology of Tetrapyrroles Gordon Research Conference (GRC) is the largest and broadest international meeting for sharing and discussing the latest research on tetrapyrroles, a diverse group of protein cofactors and metabolites which include heme, cobalamin (vitamin B12), chlorophyll, and bilins. Tetrapyrroles serve as important cofactors to control essential cellular processes important for normal homeostasis and development. In addition, tetrapyrroles also serve as a nutrient source and important signaling and regulatory molecules in normal and disease states with broad implication on human health. This meeting serves as the premier conference to present new unpublished tetrapyrrole related research findings; gather international scientists at a variety of levels including senior scientists with early stage investigators (ESI) and trainees in both formal and informal environments to create new connections and collaborations to advance the chemistry and biology of tetrapyrroles; and provide and foster an inclusive environment for the development of diverse scientists in an equitable and open setting. The 2022 GRC meeting will be held from July 17 - 22, 2022 at Salve Regina University in Newport, RI. The Chemistry & Biology of Tetrapyrroles GRC is one of a kind in terms of the international and diverse audience that it attracts. The broad diversity of topics include clinical, biological, and chemical aspects of tetrapyrroles. In addition, the range of organisms is equally as broad and spans from bacteria to humans. The 2022 GRC will integrate research from a variety of researchers at different levels in the following areas: new structural techniques to study tetrapyrroles; trafficking, signaling and regulation by heme; the many facets of bilins; tetrapyrroles in human health and disease; the biology of tetrapyrroles; the many faces of B12; the regulation and biosynthesis of chlorophyll pigments; and microbial tetrapyrrole metabolism. Given the critical roles that tetrapyrroles play in pathogenesis of infectious disease, host immunity, normal cellular development and metabolism, understanding the synthesis, regulation, degradation, and trafficking of tetrapyrroles is crucial for human health.

项目概要四吡咯化学与生物学戈登研究会议 (GRC) 是规模最大、范围最广的会议分享和讨论四吡咯（一组不同的蛋白质）最新研究的国际会议辅因子和代谢物，包括血红素、钴胺素（维生素 B12）、叶绿素和胆素。四吡咯类作为重要的辅助因子来控制对正常体内平衡很重要的基本细胞过程发展。此外，四吡咯还充当营养源和重要的信号传导和调节作用。正常和疾病状态下的分子对人类健康具有广泛的影响。此次会议作为首次会议展示新的未发表的四吡咯相关研究成果；汇聚国际不同级别的科学家，包括具有早期研究人员 (ESI) 的资深科学家以及这两个领域的实习生正式和非正式的环境，以建立新的联系和合作，以促进化学和四吡咯生物学；为多元化科学家的发展提供和培育包容性环境在公平、开放的环境中。 2022 年 GRC 会议将于 2022 年 7 月 17 日至 22 日在罗德岛州纽波特的 Salve Regina 大学举行。这四吡咯化学与生物学 GRC 在国际和多元化受众中是独一无二的它所吸引的。主题广泛多样，包括四吡咯的临床、生物学和化学方面。在此外，生物体的范围同样广泛，从细菌到人类。 2022年GRC将整合不同层次的研究人员在以下领域的研究：新结构研究四吡咯的技术；血红素的贩运、信号传递和调节；比林斯的许多方面；四吡咯对人类健康和疾病的影响；四吡咯的生物学； B12的许多面孔；规定和叶绿素色素的生物合成；和微生物四吡咯代谢。鉴于关键角色四吡咯在传染病的发病机制、宿主免疫、正常细胞发育和代谢，了解四吡咯的合成、调节、降解和运输对于人类健康。