ADVANCED FUNCTIONAL MRI EQUIPMENT FOR 3 TESLA SYSTEM: OSTEOARTHRITIS

适用于 3 Tesla 系统的先进功能 MRI 设备：骨关节炎

• 批准号: 7334961
• 负责人: RAO P GULLAPALLI
• 金额: $ 14.49万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7334961
• 关键词: anatomy; brain; community; diffusion magnetic resonance imaging; functional magnetic resonance imaging; hospitals; human; joints; knee; lead; magnetic resonance imaging; magnetism; neuroimaging; osteoarthritis; pharmacology; physiology; psychiatry; radiology; university

This subproject is one of many research subprojects utilizing the resources provided by a Shared Instrumentation Grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the grant, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): Researchers from across the campus of University of Maryland, Baltimore request funding for the purchase of Advanced Functional MRI hardware and software to enhance a 3.0 Tesla research-dedicated magnet. This newly-acquired research magnet has capabilities limited to its primary project, which is to scan knees as part of a multi-center Osteoarthritis initiative. While the scanner itself is state of the art equipment, its associated tools are very limited, and will not foster the growth of magnetic resonance research on this campus. Additionally, the scanner is idle for the most part even after fulfilling its primary objective of producing structural images of the knee joints. The lack of suitable hardware and software on this scanner has severely limited the use of this high field magnet for research. NIH sponsored investigators who are currently using magnetic resonance imaging come from various departments within the campus including radiology, neurology, psychiatry, pharmacology, cardiology, anatomy and physiology. These researchers use the clinical 1.5 Tesla scanners operated by the University of Maryland Medical System during limited hours to conduct their research. Availability of hospital scanner time for research has become increasingly difficult over the past few years due to growing clinical demand. This restrictive situation has led some of the investigators to move their research to neighboring institutions. No time is available on the hospital scanner for new investigators. The new research-dedicated 3.0 Tesla machine promises to change this situation for biomedical magnetic resonance by enhancing the research of current investigators, and increasing access to much needed MR instrumentation for new investigators. The proposed upgrade to the instrument promises to advance research in the area of human brain function through use of techniques such as fMRI, diffusion tensor imaging, and spectroscopy. The capability of performing such research in conjunction with parallel imaging with optimized coils will allow the magnetic resonance research community at the University of Maryland, Baltimore to be at the forefront of functional neuroimaging research.

该子项目是利用 NIH/NCRR 资助的共享仪器补助金提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是资助机构，不一定是研究者的机构。描述（由申请人提供）：来自巴尔的摩马里兰大学校园的研究人员请求资助购买高级功能 MRI 硬件和软件，以增强 3.0 特斯拉研究专用磁体。这家新收购的研究磁体的功能仅限于其主要项目，即扫描膝盖，作为多中心骨关节炎计划的一部分。虽然扫描仪本身是最先进的设备，但其相关工具非常有限，并且不会促进该校园磁共振研究的发展。此外，即使在实现了生成膝关节结构图像的主要目标之后，扫描仪也大部分处于闲置状态。该扫描仪缺乏合适的硬件和软件，严重限制了这种高场磁铁的研究用途。目前使用磁共振成像的美国国立卫生研究院资助的研究人员来自校园内的各个部门，包括放射学、神经学、精神病学、药理学、心脏病学、解剖学和生理学。这些研究人员在有限的时间内使用马里兰大学医疗系统运行的临床 1.5 特斯拉扫描仪进行研究。在过去几年中，由于临床需求不断增长，医院扫描仪用于研究的可用性变得越来越困难。这种限制性情况导致一些研究人员将他们的研究转移到邻近的机构。医院扫描仪上没有时间供新调查人员使用。新型研究专用 3.0 Tesla 机器有望通过加强当前研究人员的研究以及增加新研究人员获得急需的 MR 仪器的机会来改变生物医学磁共振的这种状况。拟议的仪器升级有望通过使用功能磁共振成像、扩散张量成像和光谱学等技术来推进人脑功能领域的研究。结合优化线圈的并行成像进行此类研究的能力将使巴尔的摩马里兰大学的磁共振研究界处于功能神经影像研究的前沿。