PRCC/MDACC: Partners for Excellence in Cancer Research

PRCC/MDACC：癌症研究卓越合作伙伴

• 批准号: 7500618
• 负责人: Gabriel Lopez-Berestein
• 金额: $ 45.48万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-16 至 2008-09-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7500618
• 关键词: Address; Alcohols; Appendix; Applications Grants; Appointment; Area; Award; Basic Science; Breast; Cancer Biology; Cancer Burden; Cancer Center; Cervical; Clinical; Clinical Cancer Center; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Commit; Committee Members; Communication; Communities; Community Clinical Oncology Program; Comprehensive Cancer Center; Development; Diagnostic; Doctor of Philosophy; Education and Outreach; Elements; Endometrial Carcinoma; Ensure; Epidemiology; Equipment; Eukaryotic Cell; Evaluation; Evolution; Faculty; Fellowship; Fostering; Foundations; Funding; Goals; Government; Grant; Hematologist; Hematology; Hispanics; Hospitals; Housing; Human Papillomavirus; Imaging Techniques; Incidence; Individual; Information Dissemination; Inpatients; Institution; Instruction; Insulin Resistance; Internal Medicine; Internist; Island; Joints; Laboratories; Laboratory Research; Laws; Leadership; Link; Malignant Neoplasms; Manuscripts; Medicine; Mentorship; National Cancer Program; Oncologist; Operative Surgical Procedures; Outpatients; Outreach Research; Pathology; Patients; Pharmacologic Substance; Phase; Phase II Clinical Trials; Phase III Clinical Trials; Pilot Projects; Positioning Attribute; Prevalence; Prevention; Public Health; Published Comment; Puerto Rico; RNA; Range; Recommendation; Recruitment Activity; Registries; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Residencies; Resources; Risk Factors; Role; Salaries and Fringe Benefits; Science; Scientist; Site Visit; Structure; Students; Syndrome; System; Therapeutic; Tobacco; Training; Training Programs; Training and Education; Translational Research; Universities; University of Texas M D Anderson Cancer Center; Update; Visit; Work; anticancer research; base; cancer health disparity; cancer imaging; cancer research center director; cancer risk; career; catalyst; college; design; experience; falls; interest; medical schools; member; mortality; notch protein; oncology; outreach; outreach program; professor; programs; research facility; success; symposium; treatment center; tumor; virtual

This is a resubmission for The University of Puerto Rico Comprehensive Cancer Center (UPRCCC) and The University of Texas M. D. Anderson Cancer Center (MDACC) Partnership for Excellence in Research Grant, which addresses comments and recommendations from the 1) summary statement, 2) NCI Site Visit, and 3) IAC and PSC Committees. Areas strengthened in this application include: leadership, communication, committee oversight, evaluation, career development and mentorship. Funds granted in this award will be used to: 1) support 3 full projects in cancer biology and prevention and 1 pilot project in epidemiology, 2) enhance existing collaborations and establish new collaborations, 3) increase faculty/trainee participation in the training program, 4) expand efforts in our Outreach Program to impact a larger audience, and 5) fortify and stabilize the infrastructure developing at the UPRCCC. Research grants included target 1) developing new cancer imaging techniques, 2) regulating RNA in eukaryotic cells, 3) reducing cancer risk through combined alcohol and tobacco treatment and 4) assessing the role of insulin resistance syndrome as a risk factor for endometrial cancer. The Outreach Program, which was added into the original grant mid-year 3, has been expanded to include cancer related to tobacco, as well as breast, cervical and HPV. The Training Program has also been expanded in scope to impact more faculty and trainees through a comprehensive career development and mentorship training program. The original grant (2002) was awarded to establish a comprehensive long-term mutually beneficial relationship to target and eradicate cancer health disparities. The two short term objectives of the original proposal were met: 1) develop independent cancer research investigators and 2) establish a strong working relationship based on mutual benefit, identified strengths and reciprocity. The 3rd long-term objective of the Partnership is to regain NCI-designation for the UPRCCC. Thus far, the Partnership has set the foundation for a dynamic collaboration dedicated to enhancing each partner's strengths and eliminating each partner's weaknesses. The Partnership has also served as the catalyst for two major laws passed in Puerto Rico, one of which resulted in the allocation of funding for establishing the infrastructure and recruiting top notch faculty to the UPRCCC. As of 2008, the Partnership is far from reaching its long-range goal of regaining NCI-designation for the UPRCCC. Funding for the U54 resubmission is critical to maintain the momentum of the Partnership's joint efforts in Cancer Research, Training and Outreach. RELEVANCE (See instructions): This resubmission seeks to foster and support an existing collaboration between the UPRCCC and MDACC. By addressing the differences in incidence, prevalence, mortality, and burden of cancer that exist among Hispanic populations in the US, the Partnership will strive to reduce these differences through efforts in Research, Outreach, and Training. Partnership contributions will also aid in building a stronger national cancer program through the development of a pipeline of well-trained, Hispanic cancer researchers.

这是波多黎各大学综合癌症中心（UPRCCC）和 德克萨斯大学M. D.安德森癌症中心（MDACC）研究卓越研究 格兰特（Grant 3）IAC和PSC委员会。在此应用中加强的领域包括：领导， 沟通，委员会监督，评估，职业发展和指导。授予的资金 奖项将用于：1）支持3个完整的癌症生物学和预防项目和1个试点项目 流行病学，2）增强现有合作并建立新的合作，3）增加 教师/学员参加培训计划，4）扩大我们的外展计划的努力，以影响 更大的受众群，以及5）在UPRCCC上加强并稳定基础设施。 研究补助金包括目标1）开发新的癌症成像技术，2）调节RNA 真核细胞，3）通过饮酒和烟草治疗降低癌症风险，4）评估 胰岛素抵抗综合征作为子宫内膜癌的危险因素的作用。外展计划，该计划 被添加到原始赠款3年中3中，已扩展为包括与烟草有关的癌症，因为 以及乳房，宫颈和HPV。培训计划还在范围内扩展，以影响更多 通过全面的职业发展和指导培训计划，教师和学员。 原始赠款（2002）被授予建立全面的长期互惠互利 与目标和根除癌症健康差异的关系。原始的两个短期目标 提出了建议：1）发展独立的癌症研究人员，2）建立强大的工作 基于相互利益的关系，确定的优势和互惠。第三个长期目标 合作伙伴关系是重新获得UPRCCC的NCI设计。到目前为止，伙伴关系为基础奠定了基础 进行动态合作，致力于增强每个伴侣的优势并消除每个伙伴 伴侣的弱点。该合作伙伴关系还作为两项通过的主要法律的催化剂 波多黎各，其中之一是为建立基础设施和 招募顶级教师到UPRCCC。截至2008年，伙伴关系远未达到其远程 重新获得UPRCCC的NCI设计的目标。 U54重新提交的资金对 保持伙伴关系在癌症研究，培训和外展方面的共同努力的势头。 相关性（请参阅说明）： 该重新提出旨在促进和支持UPRCCC和MDACC之间的现有合作。 通过解决存在中存在的癌症的发病率，患病率，死亡率和负担的差异 在美国的西班牙裔人口，伙伴关系将努力通过努力来减少这些差异 研究，推广和培训。伙伴关系捐款还将有助于建立更强大的国家 通过开发训练有素的西班牙癌症研究人员的癌症计划。